Target Malaria publications
Publication – January 02, 2025
A Y chromosome-linked genome editor for efficient population suppression in the malaria vector Anopheles gambiae
Publication – November 27, 2024
Unravelling the role of mitochondrial DNA in hybrid incompatibility within species of the Anopheles gambiae complex
Publication – November 26, 2024
Procedural legitimacy: co-developing a community agreement model for genetic approaches research to malaria control in Africa
Publication – October 17, 2024
The potential of gene drives in malaria vector species to control malaria in African environments
Publication – September 23, 2024
Whole-genome sequencing of major malaria vectors reveals the evolution of new insecticide resistance variants in a longitudinal study in Burkina Faso
Publication – June 12, 2024
A review of applications and limitations of using aquatic macroinvertebrate predators for biocontrol of the African malaria mosquito, Anopheles gambiae sensu lato
Publication – June 07, 2024
Y chromosome shredding in Anopheles gambiae: Insight into the cellular dynamics of a novel synthetic sex ratio distorter
Publication – May 28, 2024
Considerations for first field trials for low-threshold gene drive for malaria vector control
Publication – March 21, 2024
The population genetics of partial diapause, with applications to the aestivating malaria mosquito Anopheles coluzzii
Publication – January 05, 2024
Stakeholder engagement in the development of genetically modified mosquitoes for malaria control in West Africa
Publication – January 05, 2024
Stakeholder engagement in the development of genetically modified mosquitoes for malaria control in West Africa: lessons learned from 10 years of Target Malaria’s work in Mali
Publication – September 29, 2023
Male bias: Background strain and transgene insertion site
Publication – April 12, 2023
Defining transformation events for gene drive in species complexes
Publication – March 14, 2023
Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria mosquito
Publication – February 24, 2023
Engagement on risk assessment for gene drive mosquitoes by EFSA and Target Malaria
Publication – December 27, 2022
Gene drive designs for efficient and localisable population suppression using Y-linked editors
Publication – November 24, 2022
Analysis of the Genetic Variation of the Fruitless Gene within the Anopheles gambiae (Diptera: Culicidae) Complex Populations in Africa
Publication – October 16, 2022
Driving down malaria transmission with engineered gene drives
Publication – October 16, 2022
Introgression of a synthetic sex ratio distortion transgene into different genetic backgrounds of Anopheles coluzzii
Publication – October 16, 2022
Points to consider in seeking biosafety approval for research, testing, and environmental release of experimental genetically modified biocontrol products during research and development
Publication – August 23, 2022
A theory of resistance to multiplexed gene drive demonstrates the significant role of weakly deleterious natural genetic variation
Publication – August 05, 2022
Spatial modelling of malaria prevalence associated with geographical factors in Houet province of Burkina Faso, West Africa
Publication – July 01, 2022
Operationalizing stakeholder engagement for gene drive research in malaria elimination in Africa – translating guidance into practice
Publication – July 01, 2022
Gene drive in species complexes: defining target organisms
Publication – July 01, 2022
Comprehensive characterization of a transgene insertion in a highly repetitive, centromeric region of Anopheles mosquitoes
Publication – May 01, 2022
Recommendations for environmental risk assessment of gene drive applications for malaria vector control
Publication – April 06, 2022
A multi-disciplinary approach for a building common understanding of genetic engineering for malaria control in Burkina Faso
Publication – April 01, 2022
Life-history attributes of juvenile Anopheles gambiae s.s. in central Uganda; implications for malaria control interventions
Publication – March 01, 2022
Gene drives and population persistence vs elimination: The impact of spatial structure and inbreeding at low density
Publication – February 10, 2022
Mark-release-recapture experiment in Burkina Faso demonstrates reduced fitness and dispersal of genetically-modified sterile malaria mosquitoes
Publication – February 05, 2022
Articulating ethical principles guiding Target Malaria’s engagement strategy
Publication – January 12, 2022
Preparing an Insectary in Burkina Faso to Support Research in Genetic Technologies for Malaria Control
Publication – January 12, 2022
Local adaptation and colonization are potential factors affecting sexual competitiveness and mating choice in Anopheles coluzzii populations
Publication – December 04, 2021
The Potential for a Released Autosomal X-Shredder Becoming a Driving-Y Chromosome and Invasively Suppressing Wild Populations of Malaria Mosquitoes
Publication – October 04, 2021
Small-scale release of non-gene drive mosquitoes in Burkina Faso: from engagement implementation to assessment, a learning journey
Publication – October 04, 2021
Resistance to a CRISPR-based gene drive at an evolutionarily conserved site is revealed by mimicking genotype fixation
Publication – September 04, 2021
A systematic review assessing the potential for release of vector species from competition following insecticide-based population suppression of Anopheles species in Africa
Publication – August 15, 2021
Predatory and competitive interaction in Anopheles gambiae sensu lato larval breeding habitats in selected villages of central Uganda
Publication – July 04, 2021
Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field
Publication – May 04, 2021
Genetic Technologies for Sustainable Management of Insect Pests and Disease Vectors
Publication – May 04, 2021
Eave and swarm collections prove effective for biased captures of male Anopheles gambiae mosquitoes in Uganda
Publication – May 04, 2021
Contemporary Ne estimation using temporally spaced data with linked loci
Publication – April 01, 2021
Analysis of off-target effects in CRISPR-based gene drives in the human malaria mosquito
Publication – March 25, 2021
Ultra-conserved sequences in the genomes of highly diverse Anopheles mosquitoes, with implications for malaria vector control
Publication – March 15, 2021
Addressing key gaps in implementation of mosquito larviciding to accelerate malaria vector control in southern Tanzania: results of a stakeholder engagement process in local district councils
Publication – March 01, 2021
Systematic identification of plausible pathways to potential harm via problem formulation for investigational releases of a population suppression gene drive to control the human malaria vector Anopheles gambiae in West Africa
Publication – March 01, 2021
Proceedings of an expert workshop on community agreement for gene drive research in Africa – Co-organised by KEMRI, PAMCA and Target Malaria
Publication – March 01, 2021
Double drives and private alleles for localised population genetic control
Publication – March 01, 2021
A PCR-RFLP method for genotyping of inversion 2Rc in Anopheles coluzzii
Publication – February 15, 2021
Bulk‐up synchronization of successive larval cohorts of Anopheles gambiae and Anopheles coluzzii through temperature reduction at early larval stages: effect on emergence rate, body size and mating success
Publication – January 22, 2021
Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance
Publication – January 22, 2021
Clock genes and environmental cues coordinate Anopheles pheromone synthesis, swarming, and mating
Publication – January 22, 2021
Co-developing a common glossary with stakeholders for engagement on new genetic approaches for malaria control in a local African setting
Publication – December 22, 2020
We need to redefine the relationship between science and its end-users
Publication – October 20, 2020
Anopheles gambiae (s.l.) is found where few are looking: assessing mosquito diversity and density outside inhabited areas using diverse sampling methods
Publication – October 15, 2020
Cellular mechanisms regulating synthetic sex ratio distortion in the Anopheles gambiae germline
Publication – August 20, 2020
Modelling the suppression of a malaria vector using a CRISPR-Cas9 gene drive to reduce female fertility
Publication – July 20, 2020
Providing a policy framework for responsible gene drive research: an analysis of the existing governance landscape and priority areas for further research
Publication – June 20, 2020
Motivations and expectations driving community participation in entomological research projects: Target Malaria as a case study in Bana, Western Burkina Faso
Publication – June 20, 2020
Detecting the population dynamics of an autosomal sex-ratio distorter in a malaria vector
Publication – May 20, 2020
A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae
Publication – April 20, 2020
Auditing Preparedness for Vector Control Field Studies
Publication – April 20, 2020
The development of complex and controversial innovations. Genetically modified mosquitoes for malaria eradication
Publication – May 20, 2019
Modelling the potential of genetic control of malaria mosquitoes at national scale
Publication – May 20, 2019
Introgression of a synthetic sex ratio distortion system from Anopheles gambiae into Anopheles arabiensis
Publication – April 20, 2019
Knowledge engagement in gene drive research for malaria control
Publication – April 20, 2019
Guidance on stakeholder engagement practices to inform the development of area-wide vector control methods
Publication – April 20, 2019
Sustainable innovation in vector control requires strong partnerships with communities
Publication – February 20, 2019
Large-cage assessment of a transgenic sex-ratio distortion strain on populations of an African malaria vector
Publication – December 20, 2018
A CRISPR-Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes
Publication – July 20, 2018
Effects of the removal or reduction in density of the malaria mosquito, Anopheles gambiae s.l., on interacting predators and competitors in local ecosystems
Publication – July 02, 2018
Target Malaria welcomes the decision of the National Biosafety Agency of Burkina Faso to approve a small-scale release of genetically modified sterile male mosquitoes

Publication – June 03, 2018
Summary information note regarding the small-scale release of genetically modified sterile male mosquitoes Anopheles coluzzii strain Ac (DSM)2 in Bana village in Burkina Faso

Publication – June 03, 2018
The African Union and international experts highlight the importance of investing in sound frameworks to enable the development of gene drive for malaria control
Publication – May 13, 2018
Independent ecological risk assessment for a small-scale field release of a sterile male strain of Anopheles coluzzii
Publication – February 20, 2018
Gene Drive: Evolved and Synthetic
Publication – December 20, 2017
Gene drive to reduce malaria transmission in sub-Saharan Africa
Publication – October 20, 2017
The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito
Publication – September 21, 2017
How driving endonuclease genes can be used to combat pests and disease vectors
Publication – August 17, 2017
The use of sequential mark-release-recapture experiments to estimate population size, survival and dispersal of male mosquitoes of the Anopheles gambiae complex in Bana, a west African humid savannah village
Publication – July 18, 2017
Vector control with driving Y chromosomes: modelling the evolution of resistance
Publication – July 18, 2017
Rapid evolution of female-biased genes among four species of Anopheles malaria mosquitoes
Publication – April 18, 2017
Requirements for Driving Antipathogen Effector Genes into Populations of Disease Vectors by Homing
Publication – December 18, 2016
Impact of mosquito gene drive on malaria elimination in a computational model with explicit spatial and temporal dynamics
Publication – November 02, 2016
Target Malaria’s response to the NAS report – Target Malaria’s statement
Publication – November 02, 2016
Target Malaria’s response to the NAS report – Target Malaria’s response to the NAS report recommendation
Publication – September 18, 2016
Comparison of Model Predictions and Laboratory Observations of Transgene Frequencies in Continuously-Breeding Mosquito Populations
Publication – August 18, 2016
A CRISPR-Cas9 sex-ratio distortion system for genetic control
Publication – April 18, 2016
Gene drive through a landscape: Reaction-diffusion models of population suppression and elimination by a sex ratio distorter
Publication – January 18, 2016
A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae
Publication – December 15, 2015
Independent risk assessment for contained laboratory studies on a sterile male strain of Anopheles gambiae
Publication – November 18, 2015
Does extreme asymmetric dominance promote hybridization between Anopheles coluzzii and Anopheles gambiae s.s. in seasonal malaria mosquito communities of West Africa?
