Resistance to a CRISPR-based gene drive at an evolutionarily conserved site is revealed by mimicking genotype fixation

Posted 4th October 2021

Silke Fuchs, William T. Garrood, Anna Beber, Andrew Hammond, Roberto Galizi, Matthew Gribble, Giulia Morselli, Tin-Yu J. Hui, Katie Willis, Austin Burt, Tony Nolan and Andrea Crisanti. Resistance to a CRISPR-based gene drive at an evolutionarily conserved site is revealed by mimicking genotype fixation. PLoS Genet. 2021 Oct 5;17(10):e1009740.

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