Target Malaria established an Ethics Advisory Committee in June 2015 to advise the project on non-scientific issues related to the development of its technology. These non-scientific aspects include stakeholder engagement, regulatory process, environmental considerations and general ethical issues related to our research.
The project activities and protocols are assessed as part of usual institutional ethics review processes in the research institutes where the activities take place. While these reviews are essential to confirm that protocols are aligned with ethical guidelines and best practices, they focus on specific protocols and do not look at Target Malaria’s overall approach. Considering the innovative aspect of gene drive research, as area-wide vector control, the project felt that having an independent ethics advisory committee to provide recommendations about the non-scientific aspects of the development of the technology was important.
To reflect the diversity of perspectives and expertise needed to take a holistic view on this technology, Target Malaria has called a very diverse group of experts representing different geographies as well as aspects of ethics (bioethics, religious perspective, conservation standpoint, etc.)
The committee serves in an advisory capacity, to offer external, independent advice and recommendations. All the members serve in their individual expert capacity.
Dominic White, Chair
Dominic White, based in the UK, is Head of International Development Policy in WWF-UK with 25 years international experience in community and natural resource management in a number of countries in Africa, Asia and Central America and across a range of policy issues including international sustainable development, natural resource scarcity and climate change.
Dominic’s core skills are in strategy, team leadership, policy development, project management, and stakeholder engagement. He is co-founder and co-chair of UK Stakeholders for Sustainable Development
Dr. Abha Saxena
Dr. Abha Saxena has more than eighteen years of experience in global health and research ethics, seventeen of which have been at the World Health Organization, Geneva. As the coordinator of Global Health Ethics team at WHO, she led the development of numerous normative documents and guidelines (http://www.who.int/ethics/publications/year/en/), established a public health ethics consultative group, liaised with international organizations also working in the area of bioethics, and provided leadership to the Research ethics review committee. She led the ethics response of the Organization during the 2014-2016 Ebola outbreak in W. Africa, and the 2016 Zika Virus outbreak in Latin America. She also provided leadership to the Global Summit of National Bioethics Committees, which provides a platform for networking and exchanging experiences.
After her transition from the World Health Organization (WHO) in May 2018, Dr. Saxena has focused her attention to training, and research in global bioethics. Her areas of interest are in the ethics of infectious disease outbreaks, health systems research, healthy ageing, adolescent health care, human challenge studies, and new technologies. Currently, she has concurrent affiliation to the INCLEN Trust International, an international network of clinical epidemiologists, based in New Delhi, and University of Geneva where she is an Invited Professor.
Dr. Saxena completed her undergraduate and post graduate degrees (MBBS and MD) from the All India Institute of Medical Sciences, New Delhi, India, and is an anesthesiologist by training. She joined the faculty at the same Institute in 1986, where she taught, trained postgraduates, and conducted research in the field of anesthesiology, pain relief and palliative care till 1999. She started palliative care services at the cancer center where she worked, and was the first to support domiciliary palliative care in Delhi.
Dr. Fred Gould
Fred Gould graduated from Queens College in New York City in 1971 with a BS in Biology. In 1977, he received his PhD in Ecology and Evolutionary Biology from the State University of New York at Stony Brook with his thesis examining rapid host range evolution in a crop pest. Dr. Gould was then awarded an NSF postdoctoral fellowship to examine the relationship between insect adaptation to natural plant defenses and insecticides. He was hired as an insect ecologist at North Carolina State University in 1979 and is now a Distinguished University Professor in the Entomology and Plant Pathology Department and Co-director of the Genetic Engineering and Society Center.
Dr. Gould assisted in the development and deployment of insecticidal transgenic crops in ways that suppress the evolution of pest resistance. He is now focused on the potential for engineering insect pests to suppress disease and crop loss, and to protect species that are in danger of extinction. Dr. Gould has served on a number of US NAS-National Research Council and EPA committees addressing regulation of genetic technologies in agriculture and chaired the recent NASEM study “Genetically Engineered Crops: Past Experience and Future Prospects.” Dr. Gould received the Alexander von Humboldt award for most significant agricultural research over a five-year period, the Sigma Xi George Bugliarello Prize for written communication of science, and the O. Max Gardner Award for the University of North Carolina faculty member with the greatest contribution to human welfare. He was elected to the US National Academy of Sciences in 2011 and serves on the National Research Council Board on Agriculture and Natural Resources.
Dr. Kent H. Redford
Kent H. Redford is Principal at Archipelago Consulting established in 2012 and based in Portland, Maine, USA. Archipelago Consulting was designed to help individuals and organizations improve their practice of conservation and has worked with the Global Environment Facility, U.S. National Park Service, Moore Foundation, MacArthur Foundation, Packard Foundation and the American Zoo and Aquarium Association amongst others. Prior to Archipelago Consulting Kent spent 14 years at the Wildlife Conservation Society (WCS) in New York. Previously he spent five years as head of Science and Stewardship in The Nature Conservancy’s Latin American Division. He started his career with a decade on the faculty at University of Florida where he co-founded the Program for Studies in Tropical Conservation and the Tropical Conservation and Development Programs. He received his Ph.D. in Biology from Harvard University and has written numerous articles and books on synthetic biology and conservation, national parks, local peoples, conservation, and wildlife. He has organized and co-organized four meetings bringing together conservation biologists and synthetic biologists to discuss the future of nature in an increasingly synthetic world and currently serves as Chair of IUCN’s Task Force on Synthetic Biology and Biodiversity Conservation.
Prof. Laurie Zoloth, Ph.D.
Professor Laurie Zoloth is the Dean of the Divinity School of the University of Chicago, beginning in July 2017. She has a long and distinguished career as a bioethicist, scholar of religion, and of Jewish ethics, writing or editing 7 books, and over 300 articles.
She was elected both as President of the American Academy of Religion and as President of the American Society for Bioethics and Humanities. She was elected to the National Recombinant DNA Advisory Board in 2012. She served for two terms as member of the NASA National Advisory Board and NASA’s International Planetary Protection Advisory Committee, receiving NASA’s Distinguished Service Award. She has also been on the founding national boards of the Society for Bioethics and Humanities, the International Society for Stem Cell Research, and The Society for Scriptural Reasoning, She served as a member of four NIH DSMBs including on the Asia Aids Clinical Trials. She was the first chair of the Howard Hughes Medical Research Institute’s Bioethics Advisory Board. In 2005 she was honored as the Graduate Theological Union’s alumna of the year, and she has received distinguished teaching awards at Northwestern University and San Francisco State University.
Dr. Lydia Kapiriri
Dr. Lydia Kapiriri is an Associate professor of Global Health at McMaster University. She completed a PhD in International health from the University of Bergen- Norway and a Post- Doctoral Fellowship at the University of Toronto’s Joint Centre for Bioethics. Prior to this Dr. Kapiriri trained as Physician with specialization in public health at Makerere University- Uganda and a Masters’ in public health at the Royal Tropical Institute- Amsterdam.
Her main research interests lie in priority setting and resource allocation for health interventions and research in low income countries; with particular interest in the contextual factors, the approaches, the criteria that influence these decisions. Specifically she is interested in the equity implications of these decisions and the role of different stakeholders in these processes.
Dr. Kapiriri has served on a number of international committees as a reviewer of grant application including Grand Challenges Canada, The Canadian Institutes for Health research and advisory boards including the International Development Research Agency of Canada (IDRC)’s maternal health research program.
Prof. Maja Horst
Maja Horst is Professor of Science Communication and Head of Department of Media, Cognition and Communication at University of Copenhagen. Her research is focused on public understanding of science, social responsibility of science, management and communication of research. She has published widely, including in Public Understanding of Science, Science Communication and Social Studies of Science. In 2016 she published the book Science Communication: Culture, Identity and Citizenship co-authored with Sarah R Davies.
Maja Horst has also been experimenting with interactive science communication installations inviting citizens to discuss the social responsibility of emerging scientific fields, such as stem cell research and synthetic biology. For this she was awarded the Danish Science Minister’s Communication Prize in 2009. Since 2014 she has been a member of the Danish Science and Innovation Policy Council.
Dr. Paul Ndebele
Paul Ndebele holds a PhD in Research Ethics obtained from University of KwaZulu Natal (UKZN) in South Africa. He is currently serving as Director of the Medical Research Council Zimbabwe (MRCZ) and has prior appointments as Bioethics Contractor at the Division of AIDS, US National Institutes of Health; Assistant Director of Research Ethics, Office of Research and Development, University of Botswana; Deputy Director for Centre of Bioethics at College of Medicine, University of Malawi; and Assistant Visiting Professor at Michigan State University.
He has served as visiting scholar in various Bioethics Programmes including the Fogarty African Bioethics Programme at Johns Hopkins University; SARETI at UKZN; the Erasmus Mundus Bioethics Programme at Padova University (Italy); and Ethox Centre at Oxford University. He holds various other positions including Adjunct Professor at Africa University; Adjunct instructor at Michigan State University and Consultant/Advisor at College of Health Sciences, University of Zimbabwe. He has written widely in the area of Research Ethics and is mainly interested in issues of justice in international health research.
Dr. Rashmi L. Narayana
Rashmi currently works as Head of Clinical and Regulatory Affairs at Medopad UK. She and her team lead clinical validation of the product and manage the quality and regulatory affairs. She trained as a Psychiatrist before moving on to working as programme lead for Disaster Mental Programme with the American Red Cross. After completing a Masters in Public Health from the London School of Hygiene and Tropical Medicine she worked in academia at UCL and King’s College, London and at the London School of Economics and Political Science. She coordinated two large-scale community based Randomised Controlled Trials (RCTs) in neonatal health and primary education.
While completing her MBA at Imperial College Business School, London she worked with designers and aspiring entrepreneurs at the Royal College of Art, London to bring products to market. Her last role was Clinical Director at umotif Digital Health where she ran a RCT assessing adherence using digital health tools in Parkinson’s and was part of teams running two Real World observational studies in Parkinson’s and Arthritis. Rashmi has multiple peer-reviewed publications in to her name.
Dr. Allan R. Ronald
Allan Ronald graduated in 1961 from the University of Manitoba Faculty of Medicine. He then completed three years at the University of Maryland qualifying as a physician in Internal Medicine and three years at the University of Washington completing training and acquiring research experience in Infectious Diseases and Clinical Microbiology. He returned to Winnipeg where he established an Infectious Diseases and Clinical Microbiology 2-3 year fellowship programs. About 140 physicians have graduated from this program.
Allan’s research focused on urinary infection and sexually transmitted illnesses (STI’s). In 1979 he was invited by WHO to partner with the University of Nairobi in an effort to understand and control STI’s particularly chancroid. During the 1980’s the HIV virus was first identified and rapidly spread in Kenya. The epidemiology of heterosexual HIV was investigated by the team of Manitoba scientists and a number of effective containment measures were identified and implemented. In 2000 with Ugandan colleagues, a program was begun in Uganda to train African scientists in AIDS/HIV care with particular emphasis on antiretroviral treatment and HIV research capacity was built.
Allan served as the Head of Medical Microbiology for nine years and Head of Internal Medicine for five years at the University of Manitoba. He also been chosen for terms as President of the International Society for the Study of Sexually Transmitted Diseases and the International Society of Infectious Diseases.
Claire joined BAE Systems in January 2014 as Group Communications Director and is a member of the BAE Systems plc Executive Committee.
Before joining BAE Systems, Claire was General Manager – Group Corporate Affairs for Xstrata plc where she was responsible for the global communications of the multinational diversified mining group, including throughout the merger with Glencore International which completed in 2013. She joined Xstrata in 2004 and was also a Board member of Xstrata Nickel, one of Xstrata’s five global commodity business units.
Dr. Paulina Tindana
Dr Paulina Tindana is a bioethicist and a deputy chief health research officer at the Navrongo Health Research Centre, Ghana Health Service in northern Ghana. She received a Bachelor of Arts degree from the University of Ghana in 1999, Master of Health Sciences (Bioethics) degree from the University of Toronto, Canada in 2004 and a DPhil at the Department of Public Health, University of Oxford, UK in 2013.
Her main research interests lie in the ethics of international collaborative research, particularly the practical ethical issues arising in genetic/genomic research, informed consent, ethics review, community engagement strategies in global health research and health systems research ethics.