Development pathway

Publication
Requirements for designing cluster randomised control trials to detect suppression of malaria vector population densities

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Male bias: Background strain and transgene insertion site
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Defining transformation events for gene drive in species complexes
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Preparing an Insectary in Burkina Faso to Support Research in Genetic Technologies for Malaria Control
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A systematic review assessing the potential for release of vector species from competition following insecticide-based population suppression of Anopheles species in Africa
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Systematic identification of plausible pathways to potential harm via problem formulation for investigational releases of a population suppression gene drive to control the human malaria vector Anopheles gambiae in West Africa
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International experts report on the “Pathway to Deployment of Gene Drive Mosquitoes as a Potential Biocontrol Tool for Elimination of Malaria in Sub-Saharan Africa: Recommendations of a Scientific Working Group”
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The development of complex and controversial innovations. Genetically modified mosquitoes for malaria eradication
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The African Union’s report on “Gene Drives for malaria control and elimination in Africa”

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Target Malaria welcomes the decision of the National Biosafety Agency of Burkina Faso to approve a small-scale release of genetically modified sterile male mosquitoes
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Pathway to Deployment of Gene Drive Mosquitoes as a Potential Biocontrol Tool for Elimination of Malaria in Sub-Saharan Africa: Recommendations of a Scientific Working Group
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Report of the High-Level African Union Panel on Emerging Technologies (APET) on Gene Drives for Malaria Control and Elimination in Africa

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The African Union and international experts highlight the importance of investing in sound frameworks to enable the development of gene drive for malaria control
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malERA Refresh – An updated research agenda for malaria elimination and eradication
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Principles for gene drive research

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The African Union commits to invest in the development and regulation of gene-drive technology
