“Vector control with driving Y chromosomes: modelling the evolution of resistance” Malaria Journal, Vol:16, ISSN:1475-2875
Beaghton A, Beaghton PJ, Burt A, et al. (2017)
“Gene drive through a landscape: Reaction-diffusion models of population suppression and elimination by a sex ratio distorter” Theoretical Population Biology, Vol:108, ISSN:0040-5809, Pages:51-69
Beaghton A, Beaghton PJ, Burt A, et al. (2016)
“Impact of mosquito gene drive on malaria elimination in a computational model with explicit spatial and temporal dynamics” Proceedings of the National Academy of Sciences of the United States of America, Vol:114, ISSN:0027-8424, Pages:E255-E264
Philip A. Eckhoff, Edward A. Wenger, H. Charles J. Godfray, and Austin Burt (2016)
“Heritable strategies for controlling insect vectors of disease” Philos Trans R Soc Lond B Biol Sci; 369, 20130432 Burt, A. (2014)
“Modelling the spatial spread of a homing endonuclease gene in a mosquito population” Journal of Applied Ecology 50(5): 1216-1225 North A, Burt A, Godfray HCJ (2013)
“Requirements for effective malaria control with homing endonuclease genes” Proc. Natl. Acad. Sci. USA 108(43):E874-80 Deredec A, Godfray HC, Burt A (2011)
“Site-specific selfish genes as tools for the control and genetic engineering of natural populations” Proc. R. Soc. Lond.270: 921-928 Burt A (2003)
“MegaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering” Nucleic Acids Res. 2014 Feb;42(4):2591-601 Boissel S, Jarjour J, Astrakhan A, Adey A, Gouble A, Duchateau P, Shendure J, Stoddard BL, Certo MT, Baker D, Scharenberg AM (2014)
“Tapping natural reservoirs of homing endonucleases for targeted gene modification” Proc. Natl. Acad. Sci. USA 108(32):13077-82
Takeuchi R, Lambert AR, Mak AN, Jacoby K, Dickson RJ, Gloor GB, Scharenberg AM, Edgell DR, Stoddard BL (2011)
“High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display” Nucleic Acids Res. 37(20):6871-80
Jarjour J, West-Foyle H, Certo MT, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM (2009)
“A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes”, Nature Biotechnology (2018). Kyros Kyrou, Andrew M Hammond, Roberto Galizi, Nace Kranjc, Austin Burt, Andrea K Beaghton, Tony Nolan & Andrea Crisanti.
The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito PLOS Genetics, 2017
Andrew Hammond, Kyros Kyrou, Marco Bruttini, Ace North, Roberto Galizi, Xenia Karlsson, Nace Kranjc, Francesco M. Carpi, Romina D’Aurizio, Andrea Crisanti & Tony Nolan
“Requirements for Driving Antipathogen Effector Genes into Populations of Disease Vectors by Homing” Genetics, Vol: 205, ISSN:0016-6731, Pages:1587-1596
Andrea Beaghton, Andrew Hammond, Tony Nolan, Andrea Crisanti, H. Charles J. Godfray & Austin Burt
“A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae“ Nature Biotechnology (2016)
Andrew Hammond, Roberto Galizi, Kyros Kyrou, Alekos Simoni, Carla Siniscalchi, Dimitris Katsanos, Matthew Gribble, Dean Baker, Eric Marois, Steven Russell, Austin Burt, Nikolai Windbichler, Andrea Crisanti & Tony Nolan
“A synthetic sex ratio distortion system in the human malaria mosquito” Nature Communications; Aug 11(8):793
Galizi R, Doyle LA, Menichelli M, Bernardini F, Deredec A, Burt A, Stoddard BL, Windbichler N & Crisanti A (2014)
“Development of synthetic selfish elements based on modular nucleases in Drosophila melanogaster” Nucleic Acids Res.
Simoni A, Siniscalchi C, Chan YS, Huen DS, Russell S, Windbichler N & Crisanti A (2014)
“Site-specific genetic engineering of the Anopheles gambiae Y chromosome” PNAS; 111(21): 7600-5
Bernardini F, Galizi R, Menichelli M, Papathanos PA, Dritsou V, Marois E, Crisanti A & Windbichler N (2014)
“Insect population control by homing endonuclease-based gene drive: an evaluation in Drosophila melanogaster” Genetics 188(1):33-44
Chan YS, Naujoks DA, Huen DS, Russell S (2011)
“A synthetic homing endonuclease-based gene drive system in the human malaria mosquito” Nature 473(7346):212-5
Windbichler N, Menichelli M, Papathanos PA, Thyme SB, Li H, Ulge UY, Hovde BT, Baker D, Monnat RJ Jr, Burt A, Crisanti A (2011)
“The vasa regulatory region mediates germline expression and maternal transmission of proteins in the malaria mosquito Anopheles gambiae: a versatile tool for genetic control strategies” BMC Mol. Biol. 10:65
Papathanos PA, Windbichler N, Menichelli M, Burt A, Crisanti A (2009)
“Targeting the X chromosome during spermatogenesis induces Y chromosome transmission ratio distortion and early dominant embryo lethality in Anopheles gambiae” PLoS Genet. 4(12):e1000291
Windbichler N, Papathanos PA, Crisanti A (2008)
“Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes” Science 2 January 2015: Vol. 347 no. 6217 Daniel E. Neafsey, Robert M. Waterhouse, Mohammad R. Abai, Sergey S. Aganezov, Max A. Alekseyev, James E. Allen, James Amon, Bruno Arcà, Peter Arensburger, Gleb Artemov, Lauren A. Assour, Hamidreza Basseri, Aaron Berlin, Bruce W. Birren, Stephanie A. Blandin, Andrew I. Brockman, Thomas R. Burkot, Austin Burt, Clara S. Chan, Cedric Chauve, Joanna C. Chiu, Mikkel Christensen, Carlo Costantini, Victoria L. M. Davidson, Elena Deligianni, Tania Dottorini, Vicky Dritsou, Stacey B. Gabriel, Wamdaogo M. Guelbeogo, Andrew B. Hall, Mira V. Han, Thaung Hlaing, Daniel S. T. Hughes, Adam M. Jenkins, Xiaofang Jiang, Irwin Jungreis, Evdoxia G. Kakani, Maryam Kamali, Petri Kemppainen, Ryan C. Kennedy, Ioannis K. Kirmitzoglou, Lizette L. Koekemoer, Njoroge Laban, Nicholas Langridge, Mara K. N. Lawniczak, Manolis Lirakis, Neil F. Lobo, Ernesto Lowy, Robert M. MacCallum, Chunhong Mao, Gareth Maslen, Charles Mbogo, Jenny McCarthy, Kristin Michel, Sara N. Mitchell, Wendy Moore, Katherine A. Murphy, Anastasia N. Naumenko, Tony Nolan, Eva M. Novoa, Samantha O’Loughlin, Chioma Oringanje, Mohammad A. Oshaghi, Nazzy Pakpour, Philippos A. Papathanos, Ashley N. Peery, Michael Povelones, Anil Prakash, David P. Price, Ashok Rajaraman, Lisa J. Reimer, David C. Rinker, Antonis Rokas, Tanya L. Russell, N’Fale Sagnon, Maria V. Sharakhova, Terrance Shea, Felipe A. Simão, Frederic Simard, Michel A. Slotman, Pradya Somboon, Vladimir Stegniy, Claudio J. Struchiner, Gregg W. C. Thomas, Marta Tojo, Pantelis Topalis, José M. C. Tubio, Maria F. Unger, John Vontas, Catherine Walton, Craig S. Wilding, Judith H. Willis, Yi-Chieh Wu, Guiyun Yan, Evgeny M. Zdobnov, Xiaofan Zhou, Flaminia Catteruccia, George K. Christophides, Frank H. Collins, Robert S. Cornman, Andrea Crisanti, Martin J. Donnelly, Scott J. Emrich, Michael C. Fontaine, William Gelbart, Matthew W. Hahn, Immo A. Hansen, Paul I. Howell, Fotis C. Kafatos, Manolis Kellis, Daniel Lawson, Christos Louis, Shirley Luckhart, Marc A. T. Muskavitch, José M. Ribeiro, Michael A. Riehle, Igor V. Sharakhov, Zhijian Tu, Laurence J. Zwiebel, and Nora J. Besansky (2015)
“Extensive introgression in a malaria vector species complex revealed by phylogenomics”. Science; Jan 2;347(6217):1258524. Fontaine, M.C., Pease, J.B., Steele, A., Waterhouse, R.W., Neafsey, D.E., Sharakhov, I.V., Jiang, X., Hall, A.B., Catteruccia, F., Kakani, E., Mitchell, S.N., Wu, Y-C., Smith, H.A., Love, R.R., Lawniczak, M.K., Slotman, M.A., Emrich, S.J., Hahn, M.W., Besansky, N.J. (2015)
“Genomic Analyses of Three Malaria Vectors Reveals Extensive Shared Polymorphism but Contrasting Population Histories” Mol. Biol. Evol. 31(4):889–902 O’Loughlin SM, Magesa S, Mbogo C, Mosha F, Midega J, Lomas S, Burt A (2014)