Publications

Les travaux de recherche de Target Malaria sont publiés dans des revues scientifiques à comité de lecture et diffusés librement afin de garantir que nos résultats soient accessibles à tous. Notre bibliothèque de publications couvre nos travaux de recherche depuis les études de terrain et la recherche en laboratoire jusqu’à la modélisation et l’engagement communautaire. Découvrez ci-dessous nos derniers articles ou explorez l’intégralité de notre catalogue.

Engineering resilient gene drives for sustainable malaria control by predicting, testing and overcoming target site resistance in Anopheles gambiae
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On the use of generative models for demographic inference in malaria vectors from genomic data
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Variance partitioning reveals contrasting random effect contributions to the density and species composition of malaria-transmitting mosquitoes in western Burkina Faso
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Liste complète des publications

No. Year Date DOI PDF Title Citation Thumbnail
247 2026 06 Jul 2026 10.1073/pnas.2414207122 https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3003879&type=printable Engineering resilient gene drives for sustainable malaria control by predicting, testing and overcoming target site resistance in Anopheles gambiae Morianou I, Phillimore L, Khatri BS, Marston L, Gribble M, Burt A, Bernardini F, Hammond AM, Nolan T, Crisanti A. Engineering resilient gene drives for sustainable malaria control by predicting, testing and overcoming target site resistance in Anopheles gambiae. PLoS Biol. 2026 Jul 6;24(7):e3003879. https://targetmalaria.org/wp-content/uploads/2026/08/preview_10_1371_journal_pbio_3003879_1788166208532.png
246 2026 14 May 2026 10.1093/g3journal/jkag114 https://academic.oup.com/g3journal/article-pdf/16/7/jkag114/68284269/jkag114.pdf On the use of generative models for demographic inference in malaria vectors from genomic data Eneli AA, Siu PC, Perez MF, Burt A, Fumagalli M, Mathieson S. On the use of generative models for demographic inference in malaria vectors from genomic data. G3 (Bethesda). 2026 Jul 6;16(7):jkag114. https://targetmalaria.org/wp-content/uploads/2026/09/101093_g3journal_jkag114.png
245 2026 18 Apr 2026 10.1186/s13071-026-07406-0 https://link.springer.com/content/pdf/10.1186/s13071-026-07406-0.pdf Variance partitioning reveals contrasting random effect contributions to the density and species composition of malaria-transmitting mosquitoes in western Burkina Faso Hui TJ, Epopa PS, Millogo AA, Yao FA, Koulmaga D, Noulin F, Diabate A, Burt A. Variance partitioning reveals contrasting random effect contributions to the density and species composition of malaria-transmitting mosquitoes in western Burkina Faso. Parasit Vectors. 2026 Apr 18;19(1):235. https://targetmalaria.org/wp-content/uploads/2026/08/preview_10_1186_s13071_026_07406_0_1788166196577.png
244 2026 11 Apr 2026 10.1038/s41467-026-71627-1 https://academic.oup.com/g3journal/article-pdf/16/7/jkag114/68284269/jkag114.pdf Sex distorter male drive for resistance-resilient population control of the human malaria vector Anopheles gambiae Grilli S, Vertsimakha O, Marston L, Gonzalez IA, Burt A, Crisanti A, Bernardini F. Sex distorter male drive for resistance-resilient population control of the human malaria vector Anopheles gambiae. Nat Commun. 2026 Apr 11;17(1):5109.
243 2026 30 Mar 2026 10.1073/pnas.2535353123 https://www.pnas.org/doi/pdf/10.1073/pnas.2535353123 “Target species complex” concept: Strengthening environmental risk assessment of engineered gene drives Connolly JB, Devos Y, Glandorf DCM, Romeis J. "Target species complex" concept: Strengthening environmental risk assessment of engineered gene drives. Proc Natl Acad Sci U S A. 2026 Apr 7;123(14):e2535353123.
242 2026 01 Jan 2026 10.1093/gigascience/giag028 https://academic.oup.com/gigascience/article-pdf/doi/10.1093/gigascience/giag028/67382347/giag028.pdf Characterizing a species-rich and understudied tropical insect fauna using DNA barcoding David R Hemprich-Bennett, Ezekiel Donkor, Bernard Adams, Naana Afua Acquaah, Eva D Ofori, Samuel Anie-Amoah, Abigail Bailey, H Charles J Godfray, Owen T Lewis, Fred Aboagye-Antwi, Talya D Hackett. Characterising a species-rich and understudied tropical insect fauna using DNA barcoding. Gigascience. 2026 Mar 17:giag028.
241 2026 20 Jan 2026 10.1186/s12936-025-05768-x https://link.springer.com/content/pdf/10.1186/s12936-025-05768-x.pdf Assessing the population genetic structure and demographic history of Anopheles gambiae and Anopheles arabiensis at island and mainland sites in Uganda: implications for testing novel malaria vector control approaches Mwima R, Hui TJ, Lukyamuzi E, Bodde M, Makunin A, Birungi K, Lukindu M, Nanteza A, Muhanguzi D, Lawniczak M, Burt A, Kayondo JK. Assessing the population genetic structure and demographic history of Anopheles gambiae and Anopheles arabiensis at island and mainland sites in Uganda: implications for testing novel malaria vector control approaches. Malar J. 2026 Jan 20. https://targetmalaria.org/wp-content/uploads/2026/09/preview_10_1186_s12936_025_05768_x_1788780225182.png
240 2025 29 Oct 2025 10.1093/molbev/msaf283 https://academic.oup.com/mbe/article-pdf/42/11/msaf283/65133027/msaf283.pdf Identifying Single-Origin Rare Variants in Population Genomic Data Reynolds JJ, Koufopanou V, Burt A. Identifying Single-Origin Rare Variants in Population Genomic Data. Mol Biol Evol. 2025 Oct 29;42(11):msaf283.
239 2025 28 Oct 2025 10.1186/s13071-025-07062-w https://parasitesandvectors.biomedcentral.com/counter/pdf/10.1186/s13071-025-07062-w Semi-field experiments highlight the importance of maize and rice pollen on oviposition site choice and larval development in Anopheles arabiensis Onen H, Kaindoa EW, Akite P, Kayondo JK, Kaddumukasa MA, Akol AM, Tripet F. Semi-field experiments highlight the importance of maize and rice pollen on oviposition site choice and larval development in Anopheles arabiensis. Parasit Vectors. 2025 Oct 28;18(1):434. https://targetmalaria.org/wp-content/uploads/2026/09/preview_10_1186_s13071_025_07062_w_1788780257533.png
238 2025 27 Oct 2025 10.1038/s41467-025-64489-6 https://www.nature.com/articles/s41467-025-64489-6.pdf A male-drive female-sterile system for the self-limited control of the malaria mosquito Anopheles gambiae Strampelli A, Willis K, Gulliford HR, Gribble M, Fasulo B, Burt A, Crisanti A, Bernardini F. A male-drive female-sterile system for the self-limited control of the malaria mosquito Anopheles gambiae. Nat Commun. 2025 Oct 27;16(1):9446 https://targetmalaria.org/wp-content/uploads/2026/09/preview_10_1038_s41467_025_64489_6_1789636562798.png
237 2025 09 Oct 2025 10.1186/s12915-025-02414-5 https://bmcbiol.biomedcentral.com/counter/pdf/10.1186/s12915-025-02414-5 Requirements for designing cluster randomised control trials to detect suppression of malaria vector population densities Hancock PA, Hui TJ, Epopa PS, Milogo A, McKemey AR, Yao FA, Diabaté A, Burt A. Requirements for designing cluster randomised control trials to detect suppression of malaria vector population densities. BMC Biol. 2025 Oct 9;23(1):303.
236 2025 01 Sep 2025 10.1086/736727 Beaghton PJ, Burt A. Natural Selection of Synthetic Gene Drives for Population Suppression Can Favor an Intermediate Strength of Drive. Am Nat. 2025 Sep;206(3):206-217.
235 2025 01 Dec 2025 10.1016/j.cois.2025.101430 Genetic control strategies for population suppression in the Anopheles gambiae complex: a review of current technologies Simoni A, Tolosana I, Bernardini F. Genetic control strategies for population suppression in the Anopheles gambiae complex: a review of current technologies. Curr Opin Insect Sci. 2025 Dec;72:101430.
234 2025 28 Feb 2025 10.1186/s12889-025-21977-0 Millogo AA, Yaméogo L, Paré Toé L, Zerbo R, Ouédraogo FC, Diabaté A. Assessment of community-based resilience to malaria in two transmission settings in Western Burkina Faso. BMC Public Health. 2025 Feb 28;25(1):820.
233 2025 11 Feb 2025 10.1073/pnas.2414207122 Willis K, Burt A. Engineering drive-selection balance for localized population suppression with neutral dynamics. Proc Natl Acad Sci U S A. 2025 Feb 11;122(6):e2414207122.
232 2025 09 Jan 2025 10.1186/s12936-025-05242-8 https://malariajournal.biomedcentral.com/counter/pdf/10.1186/s12936-025-05242-8 Semi-field experiments reveal contrasted predation and movement patterns of aquatic macroinvertebrate predators of Anopheles gambiae larvae Onen H, Kaindoa EW, Nkya J, Limwagu A, Kaddumukasa MA, Okumu FO, Kayondo JK, Akol AM, Tripet F. Semi-field experiments reveal contrasted predation and movement patterns of aquatic macroinvertebrate predators of Anopheles gambiae larvae. Malar J. 2025 Jan 9;24(1):4. https://targetmalaria.org/wp-content/uploads/2026/09/preview_10_1186_s12936_025_05242_8_1789721520204.png
231 2025 02 Jan 2025 10.1038/s41467-024-55391-8 Tolosana I, Willis K, Gribble M, Phillimore L, Burt A, Nolan T, Crisanti A, Bernardini F. A Y chromosome-linked genome editor for efficient population suppression in the malaria vector Anopheles gambiae. Nat Commun. 2025 Jan 2;16(1):206.
230 2024 18 Dec 2024 10.1186/s12864-024-11127-y Kientega M, Morianou I, Traoré N, Kranjc N, Kaboré H, Zongo ON, Millogo AA, Epopa PS, Yao FA, Belem AMG, Austin B, Diabaté A. Genomic analyses revealed low genetic variation in the intron-exon boundary of the doublesex gene within the natural populations of An. gambiae s.l. in Burkina Faso. BMC Genomics. 2024 Dec 18;25(1):1207.
229 2024 27 Nov 2024 10.1038/s41598-024-80887-0 Kriezis A, Vitale M, Morselli G, Crisanti A, Bernardini F. Unravelling the role of mitochondrial DNA in hybrid incompatibility within species of the Anopheles gambiae complex. Sci Rep. 2024 Nov 27;14(1):29467.
228 2024 26 Nov 2024 10.1186/s12936-024-05160-1 Naima Sykes, Jude Bigirwenkya, Isabelle Coche, Mouhammed Drabo, Divine Dzokoto, Samantha O’Loughlin, Lea Pare Toe, Alexandre Quach, Delphine Thizy. Procedural legitimacy: co-developing a community agreement model for genetic approaches research to malaria control in Africa. Malar J 23, 359 (2024).
227 2024 17 Oct 2024 10.1038/s41467-024-53065-z Hancock PA, North A, Leach AW, Winskill P, Ghani AC, Godfray HCJ, Burt A, Mumford JD. The potential of gene drives in malaria vector species to control malaria in African environments. Nat Commun. 2024 Oct 17;15(1):8976.
226 2024 17 Sep 2024 10.1186/s12936-024-05106-7 Kientega M, Clarkson CS, Traoré N, Hui TJ, O'Loughlin S, Millogo AA, Epopa PS, Yao FA, Belem AMG, Brenas J, Miles A, Burt A, Diabaté A. Whole-genome sequencing of major malaria vectors reveals the evolution of new insecticide resistance variants in a longitudinal study in Burkina Faso. Malar J. 2024 Sep 17;23(1):280.
225 2024 12 Jun 2024 10.1186/s13071-024-06332-3 Onen H, Kaddumukasa MA, Kayondo JK, Akol AM, Tripet F. A review of applications and limitations of using aquatic macroinvertebrate predators for biocontrol of the African malaria mosquito, Anopheles gambiae sensu lato. Parasit Vectors. 2024 Jun 12;17(1):257.
224 2024 07 Jun 2024 10.1371/journal.pgen.1011303 Matteo Vitale, Nace Kranjc, Jessica Leight, Kyrous Kyrou, Thomas Courty, Louise Marston, Silvia Grilli, Andrea Crisanti, Federica Bernardini. Y chromosome shredding in Anopheles gambiae: Insight into the cellular dynamics of a novel synthetic sex ratio distorter. PLoS Genet. 2024 Jun 7;20(6):e1011303.
223 2024 22 May 2024 10.1186/s12936-024-04952-9 John B. Connolly, Abdoulaye Diabate, Austin Burt, George Christophides, Tibebu Habtewold, Anthony A. James, Jonathan K. Kayondo, Dickson Wilson Lwetoijera, Alphaxard Manjurano, Andrew R. McKemey, Mike R. Santos, Nikolai Windbichler, Filippo Randazzo. Considerations for first field trials of low-threshold gene drive for malaria vector control. Malar J 23, 156 (2024).
222 2024 21 Mar 2024 10.1186/s13071-024-06132-9 Birungi K, Mabuka DP, Balyesima V, Tripet F, Kayondo JK. Attributes of Anopheles gambiae swarms in South Central Uganda. Parasit Vectors. 2024 Mar 21;17(1):149.
221 2024 21 Mar 2024 10.1111/1755-0998.13949 Mwima R, Hui TJ, Kayondo JK, Burt A. The population genetics of partial diapause, with applications to the aestivating malaria mosquito Anopheles coluzzii. Mol Ecol Resour. 2024 Mar 21:e13949.
220 2024 05 Jan 2024 10.3389/fbioe.2023.1286694 Dicko B, Kodio S, Samoura H, Traoré F, Sykes N, Drabo M, Thizy D, Coche I, Robinson B, Sanogo K, Yagouré B, Diop S, Coulibaly MB. Stakeholder engagement in the development of genetically modified mosquitoes for malaria control in West Africa: lessons learned from 10 years of Target Malaria's work in Mali. Front Bioeng Biotechnol. 2024 Jan 5;11:1286694.
219 2023 07 Nov 2023 10.1186/s12936-023-04775-0 Mwima R, Hui TJ, Nanteza A, Burt A, Kayondo JK. Potential persistence mechanisms of the major Anopheles gambiae species complex malaria vectors in sub-Saharan Africa: a narrative review. Malar J. 2023 Nov 7;22(1):336.
218 2023 14 Aug 2023 10.1186/s12936-023-04665-5 Qureshi A, Connolly JB. Bioinformatic and literature assessment of toxicity and allergenicity of a CRISPR-Cas9 engineered gene drive to control Anopheles gambiae the mosquito vector of human malaria. Malar J. 2023 Aug 14;22(1):234.
217 2023 01 Jun 2023 10.1111/mve.12671 Bellekom B, Lewis OT, Hackett TD. Latitudinal and anthropogenic effects on the structuring of networks linking blood-feeding flies and their vertebrate hosts. Med Vet Entomol. 2023
216 2023 26 May 2023 10.3791/65356 Vitale M, Liang J, Sharakhov I, Bernardini F. Whole-Mount Fluorescence In Situ Hybridization to Study Spermatogenesis in the Anopheles Mosquito. J Vis Exp. 2023
215 2023 09 May 2023 10.1101/pdb.prot108188 Leite LN, Bascuñán P, Dotson EM, Benedict MQ. Anopheles Adult Anesthesia, Feeding, and Sex Separation. Cold Spring Harb Protoc. 2023 May 9.
214 2023 09 May 2023 10.1101/pdb.top107802 Leite LN, Bascuñán P, Dotson EM, Benedict MQ. Considerations for Rearing and Maintaining Anopheles in the Laboratory. Cold Spring Harb Protoc. 2023 May 9.
213 2023 09 May 2023 10.1101/pdb.prot108186 Leite LN, Bascuñán P, Dotson EM, Benedict MQ. Anopheles Egg Collection, Disinfection, and Hatching. Cold Spring Harb Protoc. 2023 May 9.
212 2023 09 May 2023 10.1101/pdb.prot108189 Leite LN, Bascuñán P, Dotson EM, Benedict MQ. Anopheles Pupa Collection and Sex Identification. Cold Spring Harb Protoc. 2023 May 9
211 2023 09 May 2023 10.1101/pdb.prot108187 Leite LN, Bascuñán P, Dotson EM, Benedict MQ. Anopheles Larval Rearing. Cold Spring Harb Protoc. 2023 May 9.
210 2023 12 Apr 2023 10.21203/rs.3.rs-2806607/v1 https://www.researchsquare.com/article/rs-2806607/latest.pdf Defining transformation events for gene drive in species complexes Connolly JB. Defining transformation events for gene drive in species complexes. 2023. IOBC-WPRS Bulletin 163; 88-95. Working Group “Modern Biotechnology in Integrated Plant Production”. Proceedings of the ninth Meeting at Berlin (Germany), 28-30 September, 2022. Edited by Michael Meissle, Ulrike Middelhoff, Detlef Bartsch. ISBN 978-92-9067-350-7 [XIV + 116 pp.]. https://targetmalaria.org/wp-content/uploads/2026/09/preview_10_21203_rs_3_rs_2806607_v1_1789728871857.png
209 2023 12 Apr 2023 Turner G. Assessment tools for decision making for area wide malaria vector control using gene-drive approaches – perspectives on socioeconomic considerations. 2023. IOBC-WPRS Bulletin 163; 88-95. Working Group “Modern Biotechnology in Integrated Plant Production”. Proceedings of the ninth Meeting at Berlin (Germany), 28-30 September, 2022. Edited by Michael Meissle, Ulrike Middelhoff, Detlef Bartsch. ISBN 978-92-9067-350-7 [XIV + 116 pp.].
208 2023 14 Mar 2023 10.1073/pnas.2219835120 Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria mosquito Small ST, Costantini C, Sagnon N, Guelbeogo MW, Emrich SJ, Kern AD, Fontaine MC, Besansky NJ. Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria mosquito. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2219835120.
207 2023 24 Feb 2023 10.1016/j.envsci.2023.02.009 Engagement on risk assessment for gene drive mosquitoes by EFSA and Target Malaria Hartley, S., Kokotovich, A., Devos, Y., Mumford, J. (2023) Engagement on risk assessment for gene drive mosquitoes by EFSA and Target Malaria. Environmental Science & Policy 142, 183-193.
206 2023 13 Jan 2023 10.1186/s13071-022-05607-x https://parasitesandvectors.biomedcentral.com/counter/pdf/10.1186/s13071-022-05607-x Effects of storage conditions and digestion time on DNA amplification of biting midge (Culicoides) blood meals Bellekom, B., Bailey, A., England, M. et al. Effects of storage conditions and digestion time on DNA amplification of biting midge (Culicoides) blood meals. Parasites Vectors 16, 13 (2023). https://targetmalaria.org/wp-content/uploads/2026/09/preview_10_1186_s13071_022_05607_x_1789729682195.png
205 2022 27 Dec 2022 10.1371/journal.pgen.1010550 René Geci, Katie Willis, Austin Burt. Gene drive designs for efficient and localisable population suppression using Y-linked editors. PLoS Genet. 2022 Dec 27;18(12):e1010550.
204 2022 13 Nov 2022 10.3390/insects13111048 Mahamadi Kientega, Nace Kranjc, Nouhoun Traoré, Honorine Kaboré, Dieudonné Diloma Soma, Ioanna Morianou, Moussa Namountougou, Adrien Marie Gaston Belem, Abdoulaye Diabate. Analysis of the Genetic Variation of the Fruitless Gene within the Anopheles gambiae (Diptera: Culicidae) Complex Populations in Africa. Insects. 2022 Nov 13;13(11):1048
203 2022 19 Oct 2022 10.3389/fgene.2022.891218 Garrood WT, Cuber P, Willis K, Bernardini F, Page NM, Haghighat-Khah RE. Driving down malaria transmission with engineered gene drives. Front Genet. 2022 Oct 19;13:891218.
202 2022 17 Oct 2022 10.1111/imb.12813 Pollegioni P, Persampieri T, Minuz RL, Bucci A, Trusso A, Di Martino S, Leo C, Bruttini M, Ciolfi M, Waldvogel AM, Tripet F, Simoni A, Crisanti A, Müller R. Introgression of a synthetic sex ratio distortion transgene into different genetic backgrounds of Anopheles coluzzii. Insect Mol Biol. 2022 Oct 17.
201 2022 04 Oct 2022 10.1007/s11248-022-00311-z Tonui WK, Ahuja V, Beech CJ, Connolly JB, Dass B, Glandorf DCM, James S, Muchiri JN, Mugoya CF, Okoree EA, Quemada H, Romeis J. Points to consider in seeking biosafety approval for research, testing, and environmental release of experimental genetically modified biocontrol products during research and development. Transgenic Res. 2022 Oct 4:1–17.
200 2022 09 Aug 2022 10.1073/pnas.2200567119 Khatri, BS and Burt A. A theory of resistance to multiplexed gene drive demonstrates the significant role of weakly deleterious natural genetic variation. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2200567119.
199 2022 01 Aug 2022 10.1007/s10708-022-10692-7 Abdoul Azize MILLOGO, Lassane YAMEOGO, Daouda KASSIE, François de Charles OUEDRAOGO, Charles GUISSSOU, Abdoulaye DIABATE. Spatial modelling of malaria prevalence associated with geographical factors in Houet province of Burkina Faso, West Africa. Geojournal (2022).
198 2022 23 Jul 2022 10.1186/s12936-022-04241-3 Pare Toe, L., Dicko, B., Linga, R. et al. Operationalizing stakeholder engagement for gene drive research in malaria elimination in Africa—translating guidance into practice. Malar J 21, 225 (2022).
197 2022 21 Jul 2022 10.1080/20477724.2022.2100192 Matteo Vitale, Chiara Leo, Thomas Courty, Nace Kranjc, John B. Connolly, Giulia Morselli, Christopher Bamikole, Federica Bernardini and Silke Fuchs. Comprehensive characterisation of a transgene insertion in a highly repetitive, centromeric region of Anopheles mosquitoes. Pathog Glob Health 2022 Jul 21;1-11.
196 2022 19 Jul 2022 10.1016/j.tibtech.2022.06.013 John B. Connolly, Jörg Romeis, Yann Devos, Debora C. M. Glandorf, Geoff Turner, Mamadou B. Coulibaly. Gene Drive in Species Complexes: Defining Target Organisms. Trends Biotechnol. 2022 Jul 19;S0167-7799(22)00167-6.
195 2022 25 May 2022 10.1186/s12936-022-04183-w Connolly JB, Mumford JD, Glandorf DCM, Hartley S, Lewis OT, Evans SW, Turner G, Beech C, Sykes N, Coulibaly MB, Romeis J, Teem JL, Tonui W, Lovett B, Mankad A, Mnzava A, Fuchs S, Hackett TD, Landis WG, Marshall JM, Aboagye-Antwi F. Recommendations for environmental risk assessment of gene drive applications for malaria vector control. Malar J. 2022 May 25;21(1):152.
194 2022 01 May 2022 10.20506/rst.41.1.3317 M.M. Quinlan, J.D. Mumford, S. Messori, W.R. Enkerlin, J. Shimura, S. Bishop, L. Smith, B. Dass, C. F. Oliva, C. Nelson, R. Chand & G. Torres. Issues and gaps in international guidance and national regulatory systems affecting international live insect trade. Rev Sci Tech. 2022 May;41(1):198-210.
193 2022 01 May 2022 10.20506/rst.41.1.3307 Simoni, A. Movement of genetically modified insects for research purposes. Rev Sci Tech. 2022 May;41(1):100-106.
192 2022 07 Apr 2022 10.1111/mve.12568 Batume, C., Akol, A.M., Mukwaya, L.G., Birungi, J. & Kayondo, J.K. (2022) Life-history attributes of juvenile Anopheles gambiae s.s. in central Uganda; implications for malaria control interventions. Medical and Veterinary Entomology, 36( 2), 212– 222.
191 2022 05 Apr 2022 10.1057/s41599-022-01122-7 Pare Toe, L., Barry, N., Ky, A.D. et al. A multi-disciplinary approach for building a common understanding of genetic engineering for malaria control in Burkina Faso. Humanit Soc Sci Commun 9, 117 (2022).
190 2022 03 Mar 2022 10.1016/j.tpb.2022.02.002 Beaghton PJ, Burt A. Gene drives and population persistence vs elimination: The impact of spatial structure and inbreeding at low density. Theor Popul Biol. 2022 Mar 3;145:109-125.
189 2022 10 Feb 2022 10.1038/s41467-022-28419-0 Yao FA, Millogo AA, Epopa PS, North A, Noulin F, Dao K, Drabo M, Guissou C, Kekele S, Namountougou M, Ouedraogo RK, Pare L, Barry N, Sanou R, Wandaogo H, Dabire RK, McKemey A, Tripet F, Diabaté A. Mark-release-recapture experiment in Burkina Faso demonstrates reduced fitness and dispersal of genetically-modified sterile malaria mosquitoes. Nat Commun. 2022 Feb 10;13(1):796.
188 2022 05 Feb 2022 10.1186/s12936-022-04062-4 Roberts AJ, Thizy D. Articulating ethical principles guiding Target Malaria's engagement strategy. Malar J. 2022 Feb 5;21(1):35.
187 2022 12 Jan 2022 10.1038/s41598-021-04704-8 Nignan C, Poda BS, Sawadogo SP, Maïga H, Dabiré KR, Gnankine O, Tripet F, Roux O, Diabaté A. Local adaptation and colonization are potential factors affecting sexual competitiveness and mating choice in Anopheles coluzzii populations. Sci Rep. 2022 Jan 12;12(1):636.
186 2022 06 Jan 2022 10.1089/vbz.2021.0041 Guissou C, Quinlan MM, Sanou R, Ouédraogo RK, Namountougou M, Diabaté A. Preparing an Insectary in Burkina Faso to Support Research in Genetic Technologies for Malaria Control. Vector Borne Zoonotic Dis. 2022 Jan;22(1):18-28.
185 2021 03 Dec 2021 10.3389/fbioe.2021.752253 Alcalay Y, Fuchs S, Galizi R, Bernardini F, Haghighat-Khah RE, Rusch DB, Adrion JR, Hahn MW, Tortosa P, Rotenberry R, Papathanos PA. The Potential for a Released Autosomal X-Shredder Becoming a Driving-Y Chromosome and Invasively Suppressing Wild Populations of Malaria Mosquitoes. Front Bioeng Biotechnol. 2021 Dec 3;9:752253.
184 2021 09 Oct 2021 10.1186/s12936-021-03929-2 Lea Pare Toe , Nourou Barry , Anselme D Ky , Souleymane Kekele , Wilfrid Meda, Korotimi Bayala , Mouhamed Drabo , Delphine Thizy , Abdoulaye Diabate. Small-scale release of non-gene drive mosquitoes in Burkina Faso: from engagement implementation to assessment, a learning journey. Malar J. 2021 Oct 9;20(1):395.
183 2021 05 Oct 2021 10.1371/journal.pgen.1009740 Silke Fuchs, William T. Garrood, Anna Beber, Andrew Hammond, Roberto Galizi, Matthew Gribble, Giulia Morselli, Tin-Yu J. Hui, Katie Willis, Austin Burt, Tony Nolan and Andrea Crisanti. Resistance to a CRISPR-based gene drive at an evolutionarily conserved site is revealed by mimicking genotype fixation. PLoS Genet. 2021 Oct 5;17(10):e1009740.
182 2021 08 Sep 2021 10.1186/s13071-021-04975-0 Qureshi A, Connolly JB. A systematic review assessing the potential for release of vector species from competition following insecticide-based population suppression of Anopheles species in Africa. Parasit Vectors. 2021 Sep 8;14(1):462.
181 2021 21 Aug 2021 10.1186/s13071-021-04926-9 Onen H, Odong R, Chemurot M, Tripet F, Kayondo JK. Predatory and competitive interaction in Anopheles gambiae sensu lato larval breeding habitats in selected villages of central Uganda. Parasit Vectors. 2021 Aug 21;14(1):420.
180 2021 28 Jul 2021 10.1038/s41467-021-24790-6 Hammond A, Pollegioni P, Persampieri T, North A, Minuz R, Trusso A, Bucci A, Kyrou K, Morianou I, Simoni A, Nolan T, Müller R, Crisanti A. Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field. Nat Commun. 2021 Jul 28;12(1):4589.
179 2021 26 May 2021 10.1186/s13071-021-04770-x Birungi K, Mabuka DP, Balyesima V, Namukwaya A, Chemoges EW, Kiwuwa-Muyingo S, Collins CM, Tripet F, Kayondo JK. Eave and swarm collections prove effective for biased captures of male Anopheles gambiae mosquitoes in Uganda. Parasit Vectors. 2021 May 26;14(1):281.
178 2021 18 May 2021 10.3390/su13105653 Silvia Grilli, Roberto Galizi and Chrysanthi Taxiarchi. G Genetic Technologies for Sustainable Management of Insect Pests and Disease Vectors. Sustainability 2021, 13(10), 5653
177 2021 05 May 2021 10.1111/1755-0998.13412 Hui TJ, Brenas JH, Burt A. Contemporary Ne estimation using temporally spaced data with linked loci. Mol Ecol Resour. 2021 Oct;21(7):2221-2230.
176 2021 30 Apr 2021 10.1073/pnas.2004838117 Garrood WT, Kranjc N, Petri K, Kim DY, Guo JA, Hammond AM, Morianou I, Pattanayak V, Joung JK, Crisanti A, Simoni A. Analysis of off-target effects in CRISPR-based gene drives in the human malaria mosquito. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2004838117.
175 2021 29 Mar 2021 10.1186/s12936-021-03674-6 Connolly JB, Mumford JD, Fuchs S, Turner G, Beech C, North AR, Burt A. Systematic identification of plausible pathways to potential harm via problem formulation for investigational releases of a population suppression gene drive to control the human malaria vector Anopheles gambiae in West Africa. Malar J. 2021 Mar 29;20(1):170.
174 2021 24 Mar 2021 10.12688/gatesopenres.13221.2 Thizy D, Pare Toe L, Mbogo C, Matoke-Muhia D, Alibu VP, Barnhill-Dilling SK, Chantler T, Chongwe G, Delborne J, Kapiriri L, Nassonko Kavuma E, Koloi-Keaikitse S, Kormos A, Littler K, Lwetoijera D, Vargas de Moraes R, Mumba N, Mutengu L, Mwichuli S, Nabukenya SE, Nakigudde J, Ndebele P, Ngara C, Ochomo E, Odiwuor Ondiek S, Rivera S, Roberts AJ, Robinson B, Sambakunsi R, Saxena A, Sykes N, Tarimo BB, Tiffin N, Tountas KH. Proceedings of an expert workshop on community agreement for gene drive research in Africa – Co-organised by KEMRI, PAMCA and Target Malaria. Gates Open Res. 2021 Mar 24;5:19.
173 2021 23 Mar 2021 10.1371/journal.pgen.1009333 Willis K, Burt A, Double drives and private alleles for localized population genetic control. PLoS Genet. 2021 Mar 23;17(3)
172 2021 22 Mar 2021 10.1186/s13071-021-04657-x Montanez-Gonzalez R, Vallera AC, Calzetta M, Pichler V, Love RR, Guelbeogo MW, Dabire RK, Pombi M, Costantini C, Simard F, Della Torre A, Besansky NJ. A PCR-RFLP method for genotyping of inversion 2Rc in Anopheles coluzzii. Parasit Vectors. 2021 Mar 22;14(1):174
171 2021 17 Mar 2021 10.1093/g3journal/jkab086 O'Loughlin SM, Forster AJ, Fuchs S, Dottorini T, Nolan T, Crisanti A, Burt A. Ultra-conserved sequences in the genomes of highly diverse Anopheles mosquitoes, with implications for malaria vector control. G3 (Bethesda). 2021 Mar 17:jkab086.
170 2021 02 Mar 2021 10.1186/s12936-021-03661-x Salum A. Mapua, Marceline F. Finda, Ismail H. Nambunga, Betwel J. Msugupakulya, Kusirye Ukio, Prosper P. Chaki, Frederic Tripet, Ann H. Kelly, Nicola Christofides, Javier Lezaun & Fredros O. Okumu. Addressing key gaps in implementation of mosquito larviciding to accelerate malaria vector control in southern Tanzania: results of a stakeholder engagement process in local district councils. Malar J 20, 123 (2021).
169 2021 02 Feb 2021 10.1186/s12936-021-03602-8 Zubair Q, Matthews H, Sougoufara S, Mujeeb F, Ashall S, Aboagye-Antwi F, Tripet F. Bulk-up synchronisation of successive larval cohorts of Anopheles gambiae sensu stricto and Anopheles coluzzii through temperature reduction at early larval stages: effect on emergence rates, body size and mating success. Malar J. 2021 Feb 2;20(1):67
168 2021 29 Jan 2021 10.1371/journal.pgen.1009321 Hammond A, Karlsson X, Morianou I, Kyrou K, Beaghton A, Gribble M, Kranjc N, Galizi R, Burt A, Crisanti A, Nolan T. Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance. PLoS Genet. 2021 Jan 29;17(1)
167 2021 28 Jan 2021 10.1186/s13071-020-04527-y Guindo A, Epopa P, Doumbia S, Millogo AA, Diallo B, Adama Yao F, Yagoure B, Tripet F, Diabate A, Coulibaly M. Improved Biogents Sentinel Trap configurations for outdoor collections of Anopheline species in Burkina Faso and Mali, West Africa. Parasit Vectors. 2021 Jan 28;14(1):82
166 2021 27 Jan 2021 10.21083/ibol.v11i1.6267 Hackett, TD, Logan, KE, D’Souzam ML. The important interactions behind the itch. The potential consequences of reducing anopheles gambiae mosquitoes to control malaria. iBOL Barcode Bulletin ¦ 27th January 2021
165 2021 23 Jan 2021 10.3390/insects12020097 Kranjc N, Crisanti A, Nolan T & Bernardini F. Anopheles gambiae genome conservation as a resource for rational gene drive target site selection. Insects. 2021 Jan 23;12(2):97.
164 2021 21 Jan 2021 10.1186/s12936-020-03577-y Chemonges Wanyama E, Dicko B, Pare Toe L, Coulibaly MB, Barry N, Bayala Traore K, Diabate A, Drabo M, Kayondo JK, Kekele S, Kodio S, Ky AD, Linga RR, Magala E, Meda WI, Mukwaya S, Namukwaya A, Robinson B, Samoura H, Sanogo K, Thizy D, Traoré F. Co-developing a common glossary with stakeholders for engagement on new genetic approaches for malaria control in a local African setting. Malar J. 2021 Jan 21;20(1):53
163 2021 05 Jan 2021 10.1016/j.pt.2020.12.001 Bellekom B, Hackett TD, Lewis OT. A Network Perspective on the Vectoring of Human Disease. Trends Parasitol. 2021 May;37(5):391-400. doi: 10.1016/j.pt.2020.12.001
162 2020 01 Dec 2020 10.1038/s41562-020-01023-2 Pare Toe, L. We need to redefine the relationship between science and its end-users. Nature Human Behaviour volume 5, pages176–177(2021)
161 2020 01 Dec 2020 10.1073/pnas.2018142117 Small ST, Labbé F, Lobo NF, Koekemoer LL, Sikaala CH, Neafsey DE, Hahn MW, Fontaine MC, Besansky NJ. Radiation with reticulation marks the origin of a major malaria vector. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):31583-31590.
160 2020 01 Nov 2020 Collins T, Dotson E, Benedict MQ. How can we trace malaria mosquitoes. Biomedical Science Journal for Teens – www.ScienceJournalForKids.org
159 2020 01 Nov 2020 10.1371/journal.pone.0241492 APC: Trials of the Automated Particle Dispenser for laboratory rearing of mosquito larvae. Benedict, M.Q., Bascuñán, P., Catherine Hunt, Erica Aviles, Rachel Rotenberry, Dotson, E.M. PLoS One, 2020 Nov 10;15(11)
158 2020 30 Oct 2020 10.1186/s13071-019-3877-x Montanez-Gonzalez R, Pichler V, Calzetta M, Love RR, Vallera A, Schaecher L, Caputo B, Pombi M, Petrarca V, Della Torre A, Besansky NJ. Highly specific PCR-RFLP assays for karyotyping the widespread 2Rb inversion in malaria vectors of the Anopheles gambiae complex. Parasit Vectors. 2020 Jan 10;13(1):16.
157 2020 30 Oct 2020 10.1101/gr.262790.120 Anopheles gambiae 1000 Genomes Consortium. Genome variation and population structure among 1142 mosquitoes of the African malaria vector species Anopheles gambiae and Anopheles coluzzii. Genome Res. 2020 Oct;30(10):1533-1546.
156 2020 16 Oct 2020 10.12688/wellcomeopenres.16260.2 Barbosa S, Pare Toe L, Thizy D, Vaz M, Carter L. Engagement and social acceptance in genome editing for human benefit: Reflections on research and practice in a global context. Wellcome Open Res. 2021 Jul 2;5:244.
155 2020 15 Oct 2020 10.1186/s13071-020-04403-9 Epopa PS, Millogo AA, Collins CM, North A, Benedict MQ, Tripet F, O’Loughlin S, Dabiré RK, Ouédraogo GA, Diabate A. Anopheles gambiae is found where few are looking: Assessing mosquito diversity and density outside inhabited areas using diverse sampling methods. Parasit Vectors. 2020 Oct 15;13(1):516
154 2020 13 Oct 2020 10.3390/insects11100693 Lukindu M, Love RR, Guelbeogo MW, Small ST, Stephens MT, Campbell NR, Sagnon N, Costantini C, Besansky NJ. High-Throughput Genotyping of Common Chromosomal Inversions in the Afrotropical Malaria Mosquito Anopheles Funestus. Insects. 2020 Oct 13;11(10):693.
153 2020 01 Oct 2020 10.1080/20477724.2020.1803628 Haghighat-Khah RE, Sharma A, Wunderlich MR, Morselli G, Marston LA, Bamikole C, Hall A, Kranjc N, Taxiarchi C, Sharakhov I, Galizi R. Cellular mechanisms regulating synthetic sex 1 ratio distortion in the Anopheles gambiae germline. Pathog Glob Health. 2020 Oct;114(7):370-378.
152 2020 01 Sep 2020 10.1186/s13071-020-04315-8 Hunt CM, Collins CM, Benedict MQ. Measuring and reducing biofilm in mosquito rearing containers. Parasit Vectors 2020 Sep 2;13(1):439
151 2020 01 Aug 2020 10.1186/s12915-020-00834-z North A, Burt A, Godfray HCJ. Modelling the suppression of a malaria vector using a CRISPR-Cas9 gene-drive to reduce female fertility. BMC Biol. 2020 Aug 11;18(1):98.
150 2020 01 Jul 2020 10.1186/s12936-020-03306-5 Aviles EI, Rotenberry RD, Collins CM, Dotson EM, Benedict MQ. Fluorescent markers rhodamine B and uranine for Anopheles gambiae adults and matings. Malar J. 2020 Jul 6;19(1):236
149 2020 20 Jun 2020 10.12688/wellcomeopenres.16023.1 Thizy D, Coche I, de Vries J. Providing a policy framework for responsible gene drive research: an analysis of the existing governance landscape and priority areas for further research. Wellcome Open Res. 2020 Jul 20;5:173.
148 2020 05 Jun 2020 10.1186/s12936-020-03277-7 Barry N, Toé P, Pare Toe L, Lezaun J, Drabo M, Dabiré RK, Diabate A. Motivations and expectations driving community participation in entomological research projects: Target Malaria as a case study in Bana, Western Burkina Faso. Malar J. 2020 Jun 5;19(1):199.
147 2020 01 Jun 2020 10.1186/s13071-020-04170-7 Sougoufara S, Ottih EC, Tripet F. The need for new vector control approaches targeting outdoor biting Anopheline malaria vector communities. Parasit Vectors. 2020 Jun 10;13(1):295
146 2020 01 Jun 2020 10.1111/1365-2664.13702 Pollegioni P, North A, Persampieri T, Bucci A, Minuz R, Groneberg DA, Nolan T, Papathanos P, Crisanti A, Muller R. Detecting the population dynamics of an autosomal sex-ratio distorter in a malaria vector. J Appl Ecol. 2020;00:1–11. DOI: 10.1111/1365-2664.13702
145 2020 01 May 2020 10.1038/s41587-020-0508-1 Simoni A, Hammond AM, Beaghton AK, Galizi R, Taxiarchi C, Kyrou K, Meacci D, Gribble M, Morselli G, Burt A, Nolan T, Crisanti A. A male-biased sex distorter gene drive for the human malaria vector Anopheles gambiae. Nat Biotechnol. 2020 May 11. doi: 10.1038/s41587-020-0508-1.
144 2020 01 Apr 2020 10.1016/j.respol.2019.103917 Cisnetto V, Barlow J. The development of complex and controversial innovations. Genetically modified mosquitoes for malaria control. Res Policy. 2020 Apr;49(3):103917. doi: 10.1016/j.respol.2019.103917.
143 2020 01 Mar 2020 10.1371/journal.pone.0221838 Benedict MQ, Hunt CM, Vella MG, Gonzalez KM, Dotson EM, Collins CM. Pragmatic selection of larval mosquito diets for insectary rearing of Anopheles gambiae and Aedes aegypti. PLoS One 2020 Mar 11;15(3)
142 2020 01 Feb 2020 10.1186/s12863-020-0818-9 Hui TJ, Burt A. Estimating linkage disequilibrium from genotypes under Hardy-Weinberg equilibrium. BMC Genet. 2020 Feb 26;21(1):21. doi: 10.1186/s12863-020-0818-9
141 2020 27 Jan 2020 10.4269/ajtmh.19-0710 Collins CMT, Quinlan MM. Auditing Preparedness for Vector Control Field Studies. Am J Trop Med Hyg. 2020 Apr;102(4):707-710.
140 2019 01 Nov 2019 10.1098/rspb.2019.1586 Beaghton AK, Hammond A, Nolan T, Crisanti A, Burt A. Gene drive for population genetic control? Non-functional resistance and parental effects. Proc Biol Sci. 2019 Nov 6;286(1914):20191586. doi: 10.1098/rspb.2019.1586. Epub 2019 Oct 30.
139 2019 28 Oct 2019 10.1111/eva.12878 Bergey CM, Lukindu M, Wiltshire RM, Fontaine MC, Kayondo JK, Besansky NJ. Assessing connectivity despite high diversity in island populations of a malaria mosquito. Evol Appl. 2019 Oct 28;13(2):417-431.
138 2019 07 Aug 2019 10.1534/g3.119.400445 Love RR, Redmond SN, Pombi M, Caputo B, Petrarca V, Della Torre A; Anopheles gambiae 1000 Genomes Consortium, Besansky NJ. In Silico Karyotyping of Chromosomally Polymorphic Malaria Mosquitoes in the Anopheles gambiae Complex. G3 (Bethesda). 2019 Oct 7;9(10):3249-3262.
137 2019 01 Jun 2019 10.1093/jme/tjz032 Mumford JD, Long CA, Weaver SC, Miura K, Wang E, Rotenberry R, Dotson EM, Benedict MQ. Plasmodium falciparum (Haemosporodia: Plasmodiidae) and O'nyong-nyong Virus Development in a Transgenic Anopheles gambiae (Diptera: Culicidae) Strain. J Med Entomol. 2019 Jun 27;56(4):936-941
136 2019 01 Apr 2019 10.1371/journal.pntd.0007204 Frederic Bartumeus, Guilherme B. Costa, Roger Eritja, Ann H. Kelly, Marceline Finda, Javier Lezaun, Fredros Okumu, M. Megan Quinlan, Delphine C. Thizy, Léa Paré Toé, Megan Vaughan. Sustainable innovation in vector control requires strong partnerships with communities. PLoS Negl Trop Dis. 2019 Apr; 13(4): e0007204. Published online 2019 Apr 25. doi: 10.1371/journal.pntd.0007204
135 2019 01 Apr 2019 10.1371/journal.pntd.0007286 Delphine Thizy, Claudia Emerson, Johanna Gibbs, Sarah Hartley, Lydia Kapiriri, James Lavery, Jeantine Lunshof, Janine Ramsey, Julie Shapiro, Jerome Amir Singh, Lea Pare Toe, Isabelle Coche, Benjamin Robinson. Guidance on stakeholder engagement practices to inform the development of area-wide vector control methods. PLoS Negl Trop Dis. 2019 Apr; 13(4): e0007286. Published online 2019 Apr 25. doi: 10.1371/journal.pntd.0007286
134 2019 01 Apr 2019 10.1371/journal.pntd.0007233 Sarah Hartley, Delphine Thizy, Katie Ledingham, Mamadou Coulibaly, Abdoulaye Diabaté, Bakara Dicko, Samba Diop, Jonathan Kayondo, Annet Namukwaya, Barry Nourou, Léa Paré Toé. Knowledge engagement in gene drive research for malaria control. PLoS Negl Trop Dis. 2019 Apr; 13(4): e0007233. Published online 2019 Apr 25. doi: 10.1371/journal.pntd.0007233
133 2019 01 Mar 2019 10.1038/s41598-019-41646-8 Bernardini F, Kriezis A, Galizi R, Nolan T, Crisanti A. Introgression of a synthetic sex ratio distortion system from Anopheles gambiae into Anopheles arabiensis. Sci Rep. 2019 Mar 26;9(1):5158. doi: 10.1038/s41598-019-41646-8. Erratum in: Sci Rep. 2019 May 22;9(1):7915.
132 2019 01 Mar 2019 10.1186/s12915-019-0645-5 North, A R., Burt, A., Godfray, CJH., Modelling the potential of genetic control of malaria mosquitoes at national scale. BMC Biology. 2019 Mar 29;17(1):26. doi: 10.1186/s12915-019-0645-5.
131 2019 01 Mar 2019 10.1186/s12936-019-2747-5 Epopa PS, Collins CM, North A, Millogo AA, Benedict MQ, Tripet F, Diabate A., Seasonal malaria vector and transmission dynamic in Western Burkina Faso. Malaria Journal. Malar J. 2019 Apr 2;18(1):113. doi: 10.1186/s12936-019-2747-5.
130 2019 01 Mar 2019 10.1093/molbev/msz081 Khatri B., and Burt A., Robust estimation of recent effective population size from number of independent origins in soft sweeps. Molecular Biology & Evolution. 2019 Sep 1;36(9):2040-2052. doi: 10.1093/molbev/msz081.
129 2019 01 Feb 2019 10.1186/s13071-019-3289-y Facchinelli L, North AR, Collins CM, Menichelli M, Persampieri T, Bucci A, Spaccapelo R, Crisanti A, Benedict MQ. Large-cage assessment of a transgenic sex-ratio distortion strain on populations of an African malaria vector. Parasit Vectors. 2019 Feb 6;12(1):70. doi: 10.1186/s13071-019-3289-y
128 2018 01 Dec 2018 10.1186/s13071-018-3207-8 Bernardini F, Haghighat-Khah RE, Galizi R, Hammond AM, Nolan T, Crisanti A. Molecular tools and genetic markers for the generation of transgenic sexing strains in Anopheline mosquitoes. Parasit Vectors. 2018 Dec 24;11(Suppl 2):660. doi: 10.1186/s13071-018-3207-8. Review.
127 2018 01 Sep 2018 10.1038/nbt.4245 Kyrou K, Hammond AM, Galizi R, Kranjc N, Burt A, Beaghton AK, Nolan T, Crisanti A. A CRISPR-Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes. Nat Biotechnol. 2018 Dec;36(11):1062-1066. doi: 10.1038/nbt.4245. Epub 2018 Sep 24.
126 2018 06 Aug 2018 10.1186/s12936-018-2432-0 Wiltshire RM, Bergey CM, Kayondo JK, Birungi J, Mukwaya LG, Emrich SJ, Besansky NJ, Collins FH. Reduced-representation sequencing identifies small effective population sizes of Anopheles gambiae in the north-western Lake Victoria basin, Uganda. Malar J. 2018 Aug 6;17(1):285.
125 2018 01 Jul 2018 10.1098/rspb.2018.0776 Burt A, Deredec A. Self-limiting population genetic control with sex-linked genome editors. Proc Biol Sci. 2018 Jul 25;285(1883). pii: 20180776. doi: 10.1098/rspb.2018.0776.
124 2018 01 Jun 2018 10.1111/mve.12327 Collins CM, Bonds JAS, Quinlan MM, Mumford JD. Effects of the removal or reduction in density of the malaria mosquito, Anopheles gambiae s.l., on interacting predators and competitors in local ecosystems. Med Vet Entomol. 2019 Mar;33(1):1-15.
123 2018 01 Apr 2018 10.1186/s12936-018-2288-3 North AR, Godfray HCJ. Modelling the persistence of mosquito vectors of malaria in Burkina Faso. Malar J. 2018 Apr 2;17(1):140. doi: 10.1186/s12936-018-2288-3
122 2018 01 Apr 2018 10.1186/s13071-018-2826-4 Lukindu M, Bergey CM, Wiltshire RM, Small ST, Bourke BP, Kayondo JK, Besansky NJ. Spatio-temporal genetic structure of Anopheles gambiae in the Northwestern Lake Victoria Basin, Uganda: implications for genetic control trials in malaria endemic regions. Parasit Vectors. 2018 Apr 16;11(1):246. doi: 10.1186/s13071-018-2826-4.
121 2018 01 Feb 2018 10.1021/acschembio.7b01031 Burt A, Crisanti A. Gene Drive: Evolved and Synthetic. ACS Chem Biol. 2018 Feb 16;13(2):343-346. doi: 10.1021/acschembio.7b01031. Epub 2018 Feb 5.
120 2018 01 Jan 2018 10.1089/vbz.2017.2208 Mumford JD, Leach AW, Benedict MQ, Facchinelli L, Quinlan MM. Maintaining Quality of Candidate Strains of Transgenic Mosquitoes for Studies in Containment Facilities in Disease Endemic Countries. Vector Borne Zoonotic Dis. 2018 Jan;18(1):31-38. doi: 10.1089/vbz.2017.2208.
119 2018 01 Jan 2018 10.1089/vbz.2017.2192 Quinlan MM, Mutunga JM, Diabaté A, Namountougou M, Coulibaly MB, Sylla L, Kayondo J, Balyesima V, Clark L, Benedict MQ, Raymond P. Studies of Transgenic Mosquitoes in Disease-Endemic Countries: Preparation of Containment Facilities. Vector Borne Zoonotic Dis. 2018 Jan;18(1):21-30. doi: 10.1089/vbz.2017.2192
118 2018 01 Jan 2018 10.1089/vbz.2018.29001.ben Benedict MQ, Quinlan MM. Genetically Engineered Mosquitoes for Pathogen Control. Vector Borne Zoonotic Dis. 2018 Jan;18(1):1. doi: 10.1089/vbz.2018.29001.ben
117 2018 01 Jan 2018 10.1089/vbz.2017.2189 Quinlan MM, Birungi J, Coulibaly MB, Diabaté A, Facchinelli L, Mukabana WR, Mutunga JM, Nolan T, Raymond P, Traoré SF. Containment Studies of Transgenic Mosquitoes in Disease Endemic Countries: The Broad Concept of Facilities Readiness. Vector Borne Zoonotic Dis. 2018 Jan;18(1):14-20. doi: 10.1089/vbz.2017.2189.
116 2017 01 Dec 2017 10.1080/20477724.2017.1453591 Nolan T. How to handle gene drives in arthropods. Pathog Glob Health. 2017 Dec;111(8):403. doi: 10.1080/20477724.2017.1453591. Epub 2018 Mar 28. No abstract available.
115 2017 01 Dec 2017 10.1080/20477724.2018.1453581 Burt A, Crisanti A.. Editorial: gene drive for vector control. Pathog Glob Health. 2017 Dec;111(8):397-398. doi: 10.1080/20477724.2018.1453581. Epub 2018 Mar 21.
114 2017 29 Nov 2017 10.1038/nature24995 Anopheles gambiae 1000 Genomes Consortium; Data analysis group; Partner working group; Sample collections—Angola:; Burkina Faso:; Cameroon:; Gabon:; Guinea:; Guinea-Bissau:; Kenya:; Uganda:; Crosses:; Sequencing and data production; Web application development; Project coordination. Genetic diversity of the African malaria vector Anopheles gambiae. Nature. 2017 Dec 7;552(7683):96-100.
113 2017 01 Oct 2017 10.1534/genetics.117.300221 Bernardini F, Galizi R, Wunderlich M, Taxiarchi C, Kranjc N, Kyrou K, Hammond A, Nolan T, Lawniczak MNK, Papathanos PA, Crisanti A, Windbichler N. Cross-Species Y Chromosome Function Between Malaria Vectors of the Anopheles gambiae Species Complex. Genetics. 2017 Oct;207(2):729-740. doi: 10.1534/genetics.117.300221.
112 2017 01 Oct 2017 10.1371/journal.pgen.1007039 Hammond AM, Kyrou K, Bruttini M, North A, Galizi R, Karlsson X, Kranjc N, Carpi FM, D'Aurizio R, Crisanti A, Nolan T. The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito. PLoS Genet. 2017 Oct 4;13(10):e1007039. doi: 10.1371/journal.pgen.1007039.
111 2017 01 Sep 2017 10.1186/s12915-017-0420-4 Godfray HCJ, North A, Burt A. How driving endonuclease genes can be used to combat pests and disease vectors. BMC Biol. 2017 Sep 11;15(1):81. doi: 10.1186/s12915-017-0420-4.
110 2017 01 Sep 2017 10.1101/gr.217216.116 Papa F, Windbichler N, Waterhouse RM, Cagnetti A, D'Amato R, Persampieri T, Lawniczak MKN, Nolan T, Papathanos PA. Rapid evolution of female-biased genes among four species of Anopheles malaria mosquitoes. Genome Res. 2017 Sep;27(9):1536-1548. doi: 10.1101/gr.217216.116
109 2017 01 Aug 2017 10.1186/s13071-017-2310-6 Epopa PS, Millogo AA, Collins CM, North A, Tripet F, Benedict MQ, Diabate A., “The use of sequential mark-release-recapture experiments to estimate population size, survival and dispersal of male mosquitoes of the Anopheles gambiae complex in Bana, a west African humid savannah village.”, Parasit Vectors. 2017 Aug 7;10(1):376. doi: 10.1186/s13071-017-2310-6.
108 2017 01 Jul 2017 10.1186/s12936-017-1932-7 Beaghton A, Beaghton PJ, Burt A., “Vector control with driving Y chromosomes: modelling the evolution of resistance.” Malar J. 2017 Jul 14;16(1):286. doi: 10.1186/s12936-017-1932-7.
107 2017 01 Jun 2017 10.1093/nar/gkx544 Werther R, Hallinan JP, Lambert AR, Havens K, Pogson M, Jarjour J, Galizi R, Windbichler N, Crisanti A, Nolan T, Stoddard BL., “Crystallographic analyses illustrate significant plasticity and efficient recoding of meganuclease target specificity.”, Nucleic Acids Res. 2017 Jun 20. doi: 10.1093/nar/gkx544.
106 2017 01 Apr 2017 10.1534/genetics.116.197632 Beaghton A, Hammond A, Nolan T, Crisanti A, Godfray HC, Burt A., “ Requirements for Driving Antipathogen Effector Genes into Populations of Disease Vectors by Homing.”, Genetics. 2017 Apr;205(4):1587-1596. doi: 10.1534/genetics.116.197632. Epub 2017 Feb 3.
105 2017 01 Feb 2017 10.1016/j.dci.2016.09.012 Simões ML, Dong Y, Hammond A, Hall A, Crisanti A, Nolan T, Dimopoulos G. “The Anopheles FBN9 immune factor mediates Plasmodium species-specific defense through transgenic fat body expression.”, Dev Comp Immunol. 2017 Feb;67:257-265.
104 2017 01 Feb 2017 10.1093/nar/gkw864 Jacoby K, Lambert AR, Scharenberg AM., “Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX).”, Nucleic Acids Res. 2017 Feb 17;45(3):e11. doi: 10.1093/nar/gkw864.
103 2017 01 Jan 2017 10.1073/pnas.1611064114 Eckhoff PA, Wenger EA, Godfray HC, Burt A., “Impact of mosquito gene drive on malaria elimination in a computational model with explicit spatial and temporal dynamics.“, Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):E255-E264. doi: 10.1073/pnas.1611064114.
102 2016 01 Sep 2016 10.3390/insects7040047 Valerio L, North A, Collins CM, Mumford JD, Facchinelli L, Spaccapelo R, Benedict MQ.; “Comparison of Model Predictions and Laboratory Observations of Transgene Frequencies in Continuously-Breeding Mosquito Populations”; Insects.;7(4).
101 2016 01 Aug 2016 10.1038/srep31139 Galizi R, Hammond A, Kyrou K, Taxiarchi C, Bernardini F, O'Loughlin SM, Papathanos PA, Nolan T, Windbichler N, Crisanti A.; “A CRISPR-Cas9 sex-ratio distortion system for genetic control”; Sci Rep.;6:31139.
100 2016 01 Jun 2016 10.1016/j.str.2016.03.024 Lambert AR, Hallinan JP, Shen BW, Chik JK, Bolduc JM, Kulshina N, Robins LI, Kaiser BK, Jarjour J, Havens K, Scharenberg AM, Stoddard BL.; “Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity”; Structure. 24(6):862-73.
99 2016 01 May 2016 10.1186/s12936-016-1288-4 Valerio L, Matilda Collins C, Lees RS, Benedict MQ., “Benchmarking vector arthropod culture: an example using the African malaria mosquito, Anopheles gambiae (Diptera: Culicidae).” Malar J. 2016 May 10;15(1):262. doi: 10.1186/s12936-016-1288-4.
98 2016 01 Apr 2016 10.1016/j.tpb.2015.11.005 Beaghton A, Beaghton PJ, Burt A.; “Gene drive through a landscape: Reaction-diffusion models of population suppression and elimination by a sex ratio distorter”; Theor Popul Biol.; 108:51-69.
97 2016 01 Mar 2016 10.1073/pnas.1525164113 Hall AB, Papathanos PA, Sharma A, Cheng C, Akbari OS, Assour L, Bergman NH, Cagnetti A, Crisanti A, Dottorini T, Fiorentini E, Galizi R, Hnath J, Jiang X, Koren S, Nolan T, Radune D, Sharakhova MV, Steele A, Timoshevskiy VA, Windbichler N, Zhang S, Hahn MW, Phillippy AM, Emrich SJ, Sharakhov IV, Tu ZJ, Besansky NJ.; “Radical remodeling of the Y chromosome in a recent radiation of malaria mosquitoes.” Proc Natl Acad Sci U S A.;113(15):E2114-23
96 2016 01 Mar 2016 10.1186/s12936-016-1214-9 O'Loughlin SM, Magesa SM, Mbogo C, Mosha F, Midega J, Burt A.; “Genomic signatures of population decline in the malaria mosquito Anopheles gambiae”; Malar J.;15:182.
95 2016 01 Feb 2016 10.1093/trstmh/trv113 Brady, B.J., Godfray, H.C.J., Tatem, A.J., Gething, P.W., Cohen, J.M., McKenzie, F.E., Perkins, T.A., Reiner , R.C., Tusting, L.S., Sinka, M.E., Moyes, C.L., Eckhoff, P.A., Scott, T.W., Lindsay, S.W., Hay, S.I. & Smith, D.L. “Vectorial capacity and vector control: reconsidering sensitivity to parameters for malaria elimination”; Transactions of the Royal Society of Tropical Medicine & Hygiene; 110(2):107-17.
94 2016 01 Feb 2016 10.1186/s12936-016-1107-y Deredec A, O'Loughlin SM, Hui TY, Burt A.; “Partitioning the contributions of alternative malaria vector species”; Malar J.; 15:60
93 2016 01 Jan 2016 10.1016/j.jmb.2015.12.005 Shen, B. W., Walker, B., Lambert, A., Stoddard, B. L. and Kaiser, B. K. (2015). "The structural basis of asymmetry in DNA binding and clevage as exemplified by the I-SmaMI LAGLIDADG meganuclease"; J Mol Biol.;428(1):206-20.
92 2015 01 Dec 2015 10.1038/nbt.3439 Hammond A, Galizi R, Kyrou K, Simoni A, Siniscalchi C, Katsanos D, Gribble M, Baker D, Marois E, Russell S, Burt A, Windbichler N, Crisanti A, Nolan T; “A CRISPR-Cas9 Gene Drive System Targeting Female Reproduction in the Malaria Mosquito vector Anopheles gambiae”; Nat Biotechnol.;34(1):78-83. doi: 10.1038
91 2015 01 Nov 2015 10.1186/s13071-015-1190-x Niang A, Epopa PS, Sawadogo SP, Maïga H, Konaté L, Faye O, Dabiré RK, Tripet F, Diabaté A;“Does extreme asymmetric dominance promote hybridization between Anopheles coluzzii and Anopheles gambiae s.s. in seasonal malaria mosquito communities of West Africa?”;Parasit Vectors.;8:586.
90 2015 01 Jul 2015 10.1126/science.aac7932 Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, James AA, Kaufman TC, Knoblich J, Malik HS, Matthews KA, O'Connor-Giles KM, Parks AL, Perrimon N, Port F, Russell S, Ueda R, Wildonger J.; “BIOSAFETY. Safeguarding gene drive experiments in the laboratory.” Science;349(6251):927-9
89 2015 01 Jul 2015 10.1186/s12936-015-0792-2 Facchinelli L, Valerio L, Lees RS, Oliva CF, Persampieri T, Collins CM, Crisanti A, Spaccapelo R, Benedict MQ.; “Stimulating Anopheles gambiae swarms in the laboratory: application for behavioural and fitness studies.”; Malaria J;14:271.
88 2015 01 May 2015 10.1038/mt.2015.54 Corrigan-Curay J, O'Reilly M, Kohn DB, Cannon PM, Bao G, Bushman FD, Carroll D, Cathomen T, Joung JK, Roth D, Sadelain M, Scharenberg AM, von Kalle C, Zhang F, Jambou R, Rosenthal E, Hassani M, Singh A, Porteus MH; “Genome editing technologies: defining a path to clinic”. Mol Ther.;23(5):796-806.
87 2015 01 Apr 2015 10.1534/g3.115.016808 Volohonsky G, Terenzi O, Soichot J, Naujoks DA, Nolan T, Windbichler N, Kapps D, Smidler AL, Vittu A, Costa G, Steinert S, Levashina EA, Blandin SA, Marois E.; “Tools for Anopheles gambiae Transgenesis.” G3 (Bethesda); 5(6):1151-63.
86 2015 01 Mar 2015 10.1534/genetics.115.174904 Hui TY, Burt A.; “Estimating Effective Population Size from Temporally Spaced Samples with a Novel, Efficient Maximum Likelihood Algorithm”. Genetics. 2015 Mar 5. pii: genetics.115.174904
85 2015 01 Mar 2015 10.1093/inthealth/ihv010 Brady OJ, Godfray HC, Tatem AJ, Gething PW, Cohen JM, McKenzie FE, Alex Perkins T, Reiner RC Jr, Tusting LS, Scott TW, Lindsay SW, Hay SI, Smith DL.; “Adult vector control, mosquito ecology and malaria transmission.”; Int Health. 2015 Mar;7(2):121-9.
84 2015 01 Feb 2015 10.1186/s12864-015-1257-2 Castellano L, Rizzi E, Krell J, Di Cristina M, Galizi R, Mori A, Tam J, De Bellis G, Stebbing J, Crisanti A, Nolan T.; “The germline of the malaria mosquito produces abundant miRNAs, endo-siRNAs, piRNAs and 29-nt small RNAs”. BMC Genomics
83 2015 01 Feb 2015 10.1038/nature14121 Mandell DJ, Lajoie MJ, Mee MT, Takeuchi R, Kuznetsov G, Norville JE, Gregg CJ, Stoddard BL, Church GM.; “Biocontainment of genetically modified organisms by synthetic protein design”. Nature;518(7537):55-60.
82 2015 01 Jan 2015 10.1126/science.1258522 Neafsey DE, Waterhouse RM, Abai MR, Aganezov SS, Alekseyev MA, Allen JE, Amon J, Arcà B, Arensburger P, Artemov G, Assour LA, Basseri H, Berlin A, Birren BW, Blandin SA, Brockman AI, Burkot TR, Burt A, Chan CS, Chauve C, Chiu JC, Christensen M, Costantini C, Davidson VL, Deligianni E, Dottorini T, Dritsou V, Gabriel SB, Guelbeogo WM, Hall AB, Han MV, Hlaing T, Hughes DS, Jenkins AM, Jiang X, Jungreis I, Kakani EG, Kamali M, Kemppainen P, Kennedy RC, Kirmitzoglou IK, Koekemoer LL, Laban N, Langridge N, Lawniczak MK, Lirakis M, Lobo NF, Lowy E, MacCallum RM, Mao C, Maslen G, Mbogo C, McCarthy J, Michel K, Mitchell SN, Moore W, Murphy KA, Naumenko AN, Nolan T, Novoa EM, O'Loughlin S, Oringanje C, Oshaghi MA, Pakpour N, Papathanos PA, Peery AN, Povelones M, Prakash A, Price DP, Rajaraman A, Reimer LJ, Rinker DC, Rokas A, Russell TL, Sagnon N, Sharakhova MV, Shea T, Simão FA, Simard F, Slotman MA, Somboon P, Stegniy V, Struchiner CJ, Thomas GW, Tojo M, Topalis P, Tubio JM, Unger MF, Vontas J, Walton C, Wilding CS, Willis JH, Wu YC, Yan G, Zdobnov EM, Zhou X, Catteruccia F, Christophides GK, Collins FH, Cornman RS, Crisanti A, Donnelly MJ, Emrich SJ, Fontaine MC, Gelbart W, Hahn MW, Hansen IA, Howell PI, Kafatos FC, Kellis M, Lawson D, Louis C, Luckhart S, Muskavitch MA, Ribeiro JM, Riehle MA, Sharakhov IV, Tu Z, Zwiebel LJ, Besansky NJ; “Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes”. Science. 2015 Jan 2;347(6217):1258522.
81 2015 01 Jan 2015 10.1126/science.1258524 Fontaine, M.C., Pease, J.B., Steele, A., Waterhouse, R.W., Neafsey, D.E., Sharakhov, I.V., Jiang, X., Hall, A.B., Catteruccia, F., Kakani, E., Mitchell, S.N., Wu, Y-C., Smith, H.A., Love, R.R., Lawniczak, M.K., Slotman, M.A., Emrich, S.J., Hahn, M.W., Besansky, N.J. (2014) “Extensive introgression in a malaria vector species complex revealed by phylogenomics”. Science2015 Jan 2;347(6217):1258524.
80 2015 01 Jan 2015 10.1007/978-1-4939-1862-1_6 Takeuchi R, Choi M, Stoddard BL; “Engineering of customized meganucleases via in vitro compartmentalization and in cellulo optimization”. Methods Mol Biol. 2015;1239:105-32.
79 2014 03 Nov 2014 10.1007/978-1-4939-1862-1_9 Boissel S, Scharenberg AM; “Assembly and characterization of megaTALs for hyperspecific genome engineering applications”. Methods Mol Biol. 2015;1239:171-96.
78 2014 01 Oct 2014 10.1079/9781780644516.0066 Lees R.S., D'Amato R.D., Benedict M.Q. (2014) “Inducible and Repressible Systems for Transgene Expression”. In: Transgenic Insects: Techniques and Applications. Benedict, M.Q. (ed). pp66-82. CABI, Wallingford, United Kingdom
77 2014 01 Oct 2014 10.1079/9781780644516.0306 Mumford J.D., Carrasco L.R. (2014) “Economics of transgenic insects for field release”. In: Transgenic insects: Techniques and applications. Benedict, M.Q. (ed). pp306-318. CABI, Wallingford, United Kingdom
76 2014 01 Oct 2014 10.1079/9781780644516.0283 Quinlan M.M. (2014) “Assessing risks of transgenic insects”. In: Transgenic insects: Techniques and applications. Benedict, M.Q. (ed). pp283-305. CABI, Wallingford, United Kingdom
75 2014 01 Oct 2014 10.1079/9781780644516.0000 Benedict M.Q. (ed.) "Transgenic Insects: Techniques and Applications." (2014) Published by CABI, Oxfordshire, UK; Hardback; 398 Pages; 9781780644516
74 2014 01 Sep 2014 10.1038/nmeth.3110 Scharenberg A. “Gene targeting with nucleases: capped templates, semper fidelis?” Nat Methods. 11(10):1029-30.
73 2014 01 Jul 2014 10.1038/srep05526 Fuchs S, Rende E, Crisanti A, Nolan T; “Disruption of aminergic signalling reveals novel compounds with distinct inhibitory effects on mosquito reproduction, locomotor function and survival”. Sci Rep.;4:5526
72 2014 01 Jun 2014 10.1038/ncomms4977 Galizi R, Doyle LA, Menichelli M, Bernardini F, Deredec A, Burt A, Stoddard BL, Windbichler N, Crisanti A.; “A synthetic sex ratio distortion system for the control of the human malaria mosquito”. Nat Commun.
71 2014 01 May 2014 10.1098/rstb.2013.0432 Burt, A. “Heritable strategies for controlling insect vectors of disease” Philos Trans R Soc Lond B Biol Sci 2014; 369, 20130432
70 2014 01 May 2014 10.1093/nar/gku387 Simoni A, Siniscalchi C, Chan YS, Huen DS, Russell S, Windbichler N & Crisanti A “Development of synthetic selfish elements based on modular nucleases in Drosophila melanogaster” Nucleic Acids Res.
69 2014 01 May 2014 10.1073/pnas.1404996111 Bernardini F, Galizi R, Menichelli M, Papathanos PA, Dritsou V, Marois E, Crisanti A & Windbichler N "Site-specific genetic engineering of the Anopheles gambiae Y chromosome“ PNAS 2014; 111(21): 7600-5
68 2014 01 Mar 2014 10.1093/trstmh/tru026 Smith DL, Perkins TA, Reiner RC, Niu T, Chaves LF, Ellis AM, George DB, Le Menach A, Pulliam JRC, Bisanzio D, Buckee C, Chiyaka C, Cummings DAT, Garcia AJ, Gatton ML, Gething PW, Hartley DM, Johnston G, Klein EY, Michael E, Lindsay SW, Lloyd AL, Pigott DM, Reisen WK, Ruktanonchai N, Singh B, Stoller J, Tatem AJ, Kitron U, Godfray HCJ, Cohen JM, Hay SI, Scott TW; 2014. “Recasting the theory of mosquito-borne pathogen transmission dynamics and control”. Transactions of the Royal Society of Tropical Medicine and Hygiene
67 2014 01 Mar 2014 10.1093/nar/gku224 Wang Y, Khan IF, Boissel S, Jarjour J, Pangallo J, Thyme S, Baker D, Scharenberg AM, Rawlings DJ “Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus” Nucleic Acids Res. 2014
66 2014 01 Mar 2014 10.1186/1759-8753-5-7 Stoddard BL "Homing endonucleases from mobile group I introns: discovery to genome engineering" Mob DNA. 2014; 5: 7
65 2014 01 Jan 2014 10.1093/molbev/msu040 O’Loughlin SM, Magesa S, Mbogo C, Mosha F, Midega J, Lomas S, Burt A "Genomic Analyses of Three Malaria Vectors Reveals Extensive Shared Polymorphism but Contrasting Population Histories" Mol. Biol. Evol. 31(4):889–902
64 2014 01 Jan 2014 10.1371/journal.pone.0084865 Fuchs S, Behrends V, Bundy JG, Crisanti A, Nolan T “Phenylalanine metabolism regulates reproduction and parasite melanization in the malaria mosquito” PLoS One 9(1):e84865
63 2014 01 Jan 2014 10.1007/978-1-62703-968-0_13 Jacoby K, Scharenberg AM “Homing endonuclease target determination using SELEX adapted for yeast surface display” Methods Mol Biol. 2014;1123:165-90
62 2014 01 Jan 2014 10.1007/978-1-62703-968-0_14 Baxter SK, Scharenberg AM, Lambert AR “Engineering and flow-cytometric analysis of chimeric LAGLIDADG homing endonucleases from homologous I-OnuI-family enzymes” Methods Mol Biol. 2014;1123:191-221
61 2013 01 Nov 2013 10.1093/nar/gkt1224 Boissel S, Jarjour J, Astrakhan A, Adey A, Gouble A, Duchateau P, Shendure J, Stoddard BL, Certo MT, Baker D, Scharenberg AM “MegaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering” Nucleic Acids Res. 2014 Feb;42(4):2591-601
60 2013 01 Oct 2013 10.1093/nar/gkt872 Kuhar R, Gwiazda KS, Humbert O, Mandt T, Pangallo J, Brault M, Khan I, Maizels N, Rawlings DJ, Scharenberg AM, Certo MT “Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks” Nucleic Acids Res. 2014 Jan;42(1):e4
59 2013 01 Sep 2013 10.1371/journal.pone.0074254 Chan YS, Takeuchi R, Jarjour J, Huen DS, Stoddard BL, Russell S "The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive" PLoS One. 2013 Sep 10;8(9):e74254
58 2013 01 Jul 2013 10.1111/1365-2664.12133 North A, Burt A, Godfray HCJ "Modelling the spatial spread of a homing endonuclease gene in a mosquito population" Journal of Applied Ecology 50(5): 1216-1225
57 2013 01 Apr 2013 10.1111/evo.12063 Gatton ML, Chitnis N, Churcher T, Donnelly MJ, Ghani AC, Godfray HC, Gould F, Hastings I, Marshall J, Ranson H, Rowland M, Shaman J, Lindsay SW "The importance of mosquito behavioural adaptations to malaria control in Afrcia" Evolution 67(4):1218-1230
56 2013 01 Jan 2013 10.1371/journal.pone.0054130 Chan YS, Huen DS, Glauert R, Whiteway E, Russell S "Optimising Homing Endonuclease Gene Drive Performance in a Semi-Refractory Species: The Drosophila melanogaster Experience" PLoS One 8(1):e54130
55 2013 01 Jan 2013 10.1111/1365-2656.12002 Muriu SM, Coulson T, Mbogo CM, Godfray HC "Larval density dependence in Anopheles gambiae s.s., the major African vector of malaria" J. Anim. Ecol. 82(1):166-74
54 2013 01 Jan 2013 10.1111/1365-2656.12003 Godfray HC "Mosquito ecology and control of malaria" J. Anim. Ecol. 82(1):15-25
53 2013 01 Jan 2013 10.1007/978-1-62703-293-3_4 Baxter SK, Lambert AR, Scharenberg AM, Jarjour J "Flow Cytometric Assays for Interrogating LAGLIDADG Homing Endonuclease DNA-Binding and Cleavage Properties" Methods Mol. Biol. 978:45-61
52 2012 01 Nov 2012 10.1098/rsif.2012.0253 Hancock PA, Godfray HCJ "Modelling the spread of Wolbachia in spatially heterogeneous environments" J. R. Soc. Interface 9(76):3045-54
51 2012 01 Oct 2012 10.1038/nmeth.2177 Certo MT, Gwiazda KS, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert AR, Baxter SK, Jacoby K, Ryu BY, Kiem HP, Gouble A, Paques F, Rawlings DJ, Scharenberg AM "Coupling endonucleases with DNA end-processing enzymes to drive gene disruption" Nat. Methods 9(10):973-5
50 2012 01 Sep 2012 10.1093/nar/gks502 Baxter S, Lambert AR, Kuhar R, Jarjour J, Kulshina N, Parmeggiani F, Danaher P, Gano J, Baker D, Stoddard BL, Scharenberg AM "Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases" Nucleic Acids Res. 40(16):7985-8000
49 2012 01 Jul 2012 10.1371/journal.pmed.1001262 Thomas MB, Godfray HC, Read AF, van den Berg H, Tabashnik BE, van Lenteren JC, Waage JK, Takken W "Lessons from agriculture for the sustainable management of malaria vectors" PLoS Med. 9(7):e1001262
48 2012 01 Jul 2012 10.1093/nar/gkr1303 Jacoby K, Metzger M, Shen BW, Certo MT, Jarjour J, Stoddard BL, Scharenberg AM "Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space" Nuc. Acids Res. 40 (11): 4954 – 4964
47 2012 01 Jul 2012 10.1093/nar/gks179 Ramirez CL, Certo MT, Mussolino C, Goodwin MJ, Cradick TJ, McCaffrey AP, Cathomen T, Scharenberg AM, Joung JK "Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects" Nucleic Acids Res. 40(12):5560-8
46 2012 01 May 2012 10.1186/1471-2148-12-69 Magnusson K, Lycett GJ, Mendes AM, Lynd A, Papathanos PA, Crisanti A, Windbichler N "Demasculinization of the Anopheles gambiae X chromosome" BMC Evol. Biol. 12:69
45 2012 01 May 2012 10.1093/nar/gks365 Taylor GK, Petrucci LH, Lambert AR, Baxter SK, Jarjour J, Stoddard BL "LAHEDES: the LAGLIDADG homing endonuclease database and engineering server" Nucleic Acids Research 40(Web Server issue):W110-6
44 2012 01 Mar 2012 10.1179/2047773212y.0000000003 Klein TA, Windbichler N, Deredec A, Burt A, Benedict MQ "Infertility resulting from transgenic I-PpoI male Anopheles gambiae in large cage trials" Pathog. Glob. Health 106(1):20-31
43 2012 01 Jan 2012 10.1093/nar/gkr897 Muñoz NM, Beard BC, Ryu BY, Luche RM, Trobridge GD, Rawlings DJ, Scharenberg AM, Kiem HP "Novel reporter systems for facile evaluation of I-SceI-mediated genome editing" Nucleic Acids Res. 40(2):e14
42 2011 01 Nov 2011 10.1534/genetics.111.133157 Baker DA, Russell S "Role of testis-specific gene expression in sex-chromosome evolution of Anopheles gambiae" Genetics 189(3):1117-20
41 2011 01 Oct 2011 10.1073/pnas.1110717108 Deredec A, Godfray HC, Burt A "Requirements for effective malaria control with homing endonuclease genes" Proc. Natl. Acad. Sci. USA 108(43):E874-80
40 2011 01 Aug 2011 10.1073/pnas.1104738108 Thailayil J, Magnusson K, Godfray HC, Crisanti A, Catteruccia F "Spermless males elicit large-scale female responses to mating in the malaria mosquito Anopheles gambiae" Proc. Natl. Acad. Sci. USA 108(33):13677-81
39 2011 01 Aug 2011 10.1073/pnas.1107719108 Takeuchi R, Lambert AR, Mak AN, Jacoby K, Dickson RJ, Gloor GB, Scharenberg AM, Edgell DR, Stoddard BL "Tapping natural reservoirs of homing endonucleases for targeted gene modification" Proc. Natl. Acad. Sci. USA 108(32):13077-82
38 2011 01 Jul 2011 10.1038/nmeth.1648 Certo MT, Ryu BY, Annis JE, Garibov M, Jarjour J, Rawlings DJ, Scharenberg AM "Tracking genome engineering outcome at individual DNA breakpoints" Nat. Methods 8(8):671-6
37 2011 01 Jun 2011 10.1371/journal.pone.0021572 Magnusson K, Mendes AM, Windbichler N, Papathanos PA, Nolan T, Dottorini T, Rizzi E, Christophides GK, Crisanti A "Transcription regulation of sex-biased genes during ontogeny in the malaria vector Anopheles gambiae" PLoS One 6(6):e21572
36 2011 01 Jun 2011 10.1186/1471-2164-12-296 Baker DA, Nolan T, Fischer B, Pinder A, Crisanti A, Russell S "A comprehensive gene expression atlas of sex- and tissue-specificity in the malaria vector, Anopheles gambiae" BMC Genomics 12:296
35 2011 01 May 2011 10.1038/nature09937 Windbichler N, Menichelli M, Papathanos PA, Thyme SB, Li H, Ulge UY, Hovde BT, Baker D, Monnat RJ Jr, Burt A, Crisanti A "A synthetic homing endonuclease-based gene drive system in the human malaria mosquito" Nature 473(7346):212-5
34 2011 01 May 2011 10.1534/genetics.111.127506 Chan YS, Naujoks DA, Huen DS, Russell S "Insect population control by homing endonuclease-based gene drive: an evaluation in Drosophila melanogaster" Genetics 188(1):33-44
33 2011 01 Apr 2011 10.1371/journal.pntd.0001024 Hancock PA, Sinkins SP, Godfray HCJ "Strategies for introducing Wolbachia to reduce transmission of mosquito-borne diseases" PLoS Neglected Tropical Diseases 5(4):e1024
32 2011 01 Mar 2011 10.1086/658121 Hancock PA, Sinkins SP, Godfray HCJ "Population dynamic models of the spread of Wolbachia" American Naturalist 177, 323-333
31 2011 01 Feb 2011 10.1371/journal.pone.0016825 Aubert M, Ryu BY, Banks L, Rawlings DJ, Scharenberg AM, Jerome KR "Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonucleases Y2 I-AniI" PLoS One 6(2):e16825
30 2011 01 Feb 2011 10.1371/journal.pone.0016471 Nolan T, Petris E, Müller HM, Cronin A, Catteruccia F, Crisanti A "Analysis of two novel midgut-specific promoters driving transgene expression in Anopheles stephensi mosquitoes" PLoS One 6(2):e16471
29 2011 01 Jan 2011 10.1007/s10709-010-9482-8 Nolan T, Papathanos P, Windbichler N, Magnusson K, Benton J, Catteruccia F, Crisanti A "Developing transgenic Anopheles mosquitoes for the sterile insect technique" Genetica 139(1):33-9
28 2010 01 Dec 2010 10.1186/1756-3305-3-117 Sinka ME, Bangs MJ, Manguin S, Coetzee M, Mbogo CM, Hemingway J, Patil AP, Temperley WH, Gething PW, Kabaria CW, Okara RM, Van Boeckel T, Godfray HC, Harbach RE, Hay SI "The dominant Anopheles vectors of human malaria in Africa, Europe and the Middle East: occurrence data, distribution maps and bionomic précis" Parasit. Vectors 3:117
27 2010 01 Sep 2010 10.1093/nar/gkq283 Ashworth J, Taylor GK, Havranek JJ, Quadri SA, Stoddard BL, Baker D "Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs" Nuc. Acids Res. 38 (16) 5601 – 5608
26 2010 01 Jun 2010 10.1186/1471-2105-11-359 Huen D, Russell S "On the use of resampling tests for evaluating statistical significance of binding-site co-occurrence" BMC Bioinformatics 11:359
25 2010 01 Jun 2010 10.1007/s11248-009-9323-7 Rémy S, Tesson L, Ménoret S, Usal C, Scharenberg AM, Anegon I "Zinc-finger nucleases: a powerful tool for genetic engineering of animals" Transgenic Res. 19(3):363-71
24 2010 01 Feb 2010 10.1371/journal.pmed.1000209 Hay SI, Sinka ME, Okara RM, Kabaria CW, Mbithi PM, Tago CC, Benz D, Gething PW, Howes RE, Patil AP, Temperley WH, Bangs MJ, Chareonviriyaphap T, Elyazar IR, Harbach RE, Hemingway J, Manguin S, Mbogo CM, Rubio-Palis Y, Godfray HC "Developing global maps of the dominant anopheles vectors of human malaria" PLoS Med. 7(2):e1000209
23 2009 01 Nov 2009 10.1186/1475-2875-8-s2-s5 Papathanos PA, Bossin HC, Benedict MQ, Catteruccia F, Malcolm CA, Alphey L, Crisanti A "Sex separation strategies: past experience and new approaches" Malar. J. 8 Suppl 2:S5
22 2009 01 Nov 2009 10.1093/nar/gkp726 Jarjour J, West-Foyle H, Certo MT, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM "High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display" Nucleic Acids Res. 37(20):6871-80
21 2009 01 Oct 2009 10.1038/nature08508 Thyme SB, Jarjour J, Takeuchi R, Havranek JJ, Ashworth J, Scharenberg AM, Stoddard BL, Baker D "Exploitation of binding energy for catalysis and design" Nature 461(7268):1300-4
20 2009 01 Jul 2009 10.1186/1471-2199-10-65 Papathanos PA, Windbichler N, Menichelli M, Burt A, Crisanti A "The vasa regulatory region mediates germline expression and maternal transmission of proteins in the malaria mosquito Anopheles gambiae: a versatile tool for genetic control strategies" BMC Mol. Biol. 10:65
19 2009 01 May 2009 10.1186/1471-2164-10-242 Baker DA, Russell S "Gene expression during Drosophila melanogaster egg development before and after reproductive diapause" BMC Genomics 10(1):242
18 2009 01 Apr 2009 10.1093/nar/gkp004 Li H, Pellenz S, Ulge U, Stoddard BL, Monnat RJ Jr "Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins" Nucleic Acids Research 37 (5): 1650 – 1662
17 2009 01 Mar 2009 10.1073/pnas.0810588106 McConnell-Smith A, Takeuchi R, Pellenz S, Davis L, Maizels N, Monnat RJ Jr, Stoddard BL "Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease" PNAS USA 106 (13): 5099-104
16 2009 01 Feb 2009 10.1093/nar/gkn1007 Takeuchi R, Certo M, Caprara MG, Scharenberg AM, Stoddard BL "Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation" Nucleic Acids Res. 37(3):877-90
15 2009 01 Jan 2009 10.1098/rspb.2008.0689 Hancock PA, Thomas MB, Godfray HCJ "An age-structured model to evaluate the potential of novel malaria control interventions using fungal entomopathogen sprays" Proc. Biol. Sci. 276(1654): 71–80
14 2008 01 Dec 2008 10.1098/rspb.2008.0914 Jansen VA, Turelli M, Godfray HCJ "Stochastic spread of Wolbachia" Proceedings of the Royal Society of London B 275, 2769-2776
13 2008 01 Dec 2008 10.1371/journal.pgen.1000291 Windbichler N, Papathanos PA, Crisanti A "Targeting the X chromosome during spermatogenesis induces Y chromosome transmission ratio distortion and early dominant embryo lethality in Anopheles gambiae" PLoS Genet. 4(12):e1000291
12 2008 01 Dec 2008 10.1093/nar/gkn846 Nomura N, Nomura Y, Sussman D, Klein D, Stoddard BL "Recognition of a common rDNA target site by analogous archael LAGLIDADG and eukaryal His-Cys box homing endonucleases isoschizomers" Nucleic Acids Research 36 (22): 6988 – 6998
11 2008 01 Aug 2008 10.1534/genetics.108.089037 Deredec A, Burt A, Godfray HCJ "The population genetics of using homing endonuclease genes in vector and pest management" Genetics 179(4):2013-26
10 2007 01 Dec 2007 10.1186/1471-2164-8-454 Baker DA, Meadows LA, Wang J, Dow JAT, Russell S "Variable sexually dimorphic gene expression in laboratory strains of Drosophila melanogaster" BMC Genomics 8:454
9 2007 01 Oct 2007 10.1016/j.jmb.2007.07.052 Scalley-Kim M, McConnell-Smith A, Stoddard BL "Coevolution of homing endonuclease specificity and its host target sequence" J. Mol. Biol. 372 (5): 1305 – 1319
8 2007 01 Aug 2007 10.1093/nar/gkm632 Windbichler N, Papathanos PA, Catteruccia F, Ranson H, Burt A, Crisanti A "Homing endonuclease mediated gene targeting in Anopheles gambiae cells and embryos" Nucleic Acids Research 35(17):5922-33
7 2007 01 Aug 2007 10.1093/nar/gkm867 Eastberg JH, McConnell-Smith A, Zhao L, Ashworth J, Shen BW, Stoddard BL "The thermodynamics of DNA target site recognition by homing endonucleases" Nuc. Acids Res. 35 (21) 7209 – 7221
6 2007 01 Jul 2007 10.1186/1475-2875-6-98 Hancock PA, Godfray HCJ "Application of the lumped age-class technique to studying the dynamics of malaria-mosquito-human interactions" Malaria J. 6:98
5 2007 01 Apr 2007 10.1093/nar/gkm182 Volná P, Jarjour J, Baxter S, Roffler SR, Monnat RJ Jr, Stoddard BL, Scharenberg AM "Flow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleases" Nucleic Acids Research 35(8):2748-2758
4 2006 01 Oct 2006 10.1093/nar/gkl645 Rosen LE, Morrison HA, Masri S, Brown MJ, Springstubb B, Sussman D, Stoddard BL, Seligman LM "Homing endonuclease I-CreI derivatives with novel DNA target specificities" Nuc. Acids Research 34 (17): 4791 – 800
3 2006 01 Jun 2006 10.1038/nature04818 Ashworth J, Havranek JJ, Duarte CM, Sussman D, Monnat RJ Jr, Stoddard BL, Baker D "Computational redesign of endonuclease DNA binding and cleavage specificity" Nature 441: 656 – 659
2 2006 01 May 2006 10.1016/j.str.2006.03.009 Spiegel PC, Chevalier B, Sussman D, Turmel M, Lemieux, Stoddard BL "The structure of I-CeuI homing endonuclease: evolving asymmetric DNA recognition from a symmetric protein scaffold" Structure 14 (5): 869 – 880
1 2005 01 Nov 2005 10.1038/nbt1152 Catteruccia F, Benton JP, Crisanti A "An Anopheles transgenic sexing strain for vector control" Nature Biotechnology (2005) 23, 1414 – 1417

Publications par année

La forte augmentation du nombre de publications entre 2020 et 2022 reflète l’impact des restrictions liées à la COVID-19, qui ont limité les travaux sur le terrain et en laboratoire et ont conduit les chercheurs à consacrer davantage de temps à la rédaction et à la publication de leurs résultats existants.