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Blog – 15 November 2024

COP 16 highlights: A new path for peace with nature

...the Convention and the implementation of the Kunming-Montreal Global Biodiversity Framework (KMGBF). A key highlight of COP 16 was the growing focus on the interlinkages between biodiversity and health. Parties approved a Global Action...

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Blog – 07 November 2024

What do genetically modified mosquitoes look like? 

...find out more about genetically modified mosquitoes and how they could contribute to reduce malaria transmission. https://www.youtube.com/watch?v=aQG97URrEOU For more information about Target Malaria’s work at the CDC Foundation, click here....

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Blog – 25 October 2024

Embracing innovation in science reporting: My journey and reflections 

...opportunities. With increased access to information and platforms, there’s a rising demand for insightful reporting on health innovations. Social media and online platforms have transformed how we disseminate information, allowing...

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Media Coverage – 16 October 2024

La génomique au service de la lutte contre le paludisme

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Media Coverage – 16 October 2024

Using genomics to find solutions to malaria

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Media Coverage – 08 October 2024

Professor Abdoulaye Diabaté’s frank conversation with Bill Gates

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Blog – 03 October 2024

How to dissect a mosquito 

...are pointing at some of the oocysts, indicating the mosquito was infected with the malaria parasite.   https://www.youtube.com/watch?v=AIF8_ohJ7yY To find out more about Target Malaria’s work at the CDC Foundation, please...

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Press Release – 27 September 2024

Finishing off Malaria: Professor Abdoulaye Diabaté’s frank conversation with Bill Gates

...streaming site Netflix. ENDS For more information: Netflix documentary series: https://www.netflix.com/fr-en/title/81609333?trkid=258593161&s=i&vlang=en Prof. Abdoulaye Diabaté’s blog post about the show: https://targetmalaria.org/latest/news/finishing-off-malaria-my-conversation-with-bill-gates/ [1] World Malaria Report (2023), WHO [2] The WHO Global...

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Multimedia – 19 September 2024

Episode 5: Can we outsmart disease?

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Media Coverage – 16 September 2024

Journée internationale du Moustique 2024 sur Info Matin

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Spokeperson – 16 September 2024

Jean Windéyam Birba

Jean Windéyam Birba is National Stakeholder Engagement Manager for Target Malaria Burkina Faso at the Institut de Recherche en Sciences de la Santé (IRSS)/Centre Muraz in Bobo-Dioulasso, Burkina Faso. A...

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Media Coverage – 16 September 2024

Experts discuss role of gene modification in combating malaria

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Media Coverage – 16 September 2024

Dengue or malaria? Distinguishing mosquito-borne diseases?

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Media Coverage – 09 September 2024

On the fight against malaria

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News – 05 September 2024

Burkina Faso’s National Biosafety Agency states its support to Target Malaria

...Malaria project), and Aedes mosquitoes, the vectors of dengue fever”. Full release (in French): https://www.infosciencesculture.com/en/node/219 Target Malaria supports and scrupulously respects stringent, competent, responsible and transparent regulations to advance research into...

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Media Coverage – 21 August 2024

The Weight of Malaria: Silent Crisis in Hoima

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Photo of Prof. Diabate

Media Coverage – 20 August 2024

Pr Abdoulaye Diabaté, investigateur principal du projet Target Malaria Burkina Faso : « Nous devrions être en mesure d’éliminer le paludisme dans un futur plus ou moins proche »

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Graphic showing different mosquito genuses including aedes, culiseta, psorophora, toxorhynchites, anopheles nnd culex

Media Coverage – 20 August 2024

Mosquito-Borne Diseases Rise Amidst Climate Change, Experts Warn

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A scan of mosquitos under a microscope

Media Coverage – 07 August 2024

Are we entering a new era of mosquito control?

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Media Coverage – 21 July 2024

Une délégation de l’Académie des Sciences visite le site de recherche du projet « Target Malaria »

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Jobs – 15 July 2024

Research Associate in Genetic Vector Control

...applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/  The College believes that the use of animals in research is...

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Media Coverage – 15 July 2024

Diabaté: Malaria is tightly linked to poverty

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Image of a mosquito by the Financial Times

Media Coverage – 18 June 2024

The race against time to defeat mosquito-borne diseases

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A woman with braided hair, wearing a black outfit and carrying a black bag, smiles while standing outside with several children nearby. The background features colorful, overlapping circles and the text at the bottom reads, "and I am fighting to end malaria in Uganda.

Multimedia – 03 June 2024

Global Fund Fight For What Counts – Krystal Birungi

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Multimedia – 28 May 2024

How do you solve a problem like malaria?

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Multimedia – 05 May 2024

(Un)natural Selection, episode 3: Changing an Entire Species

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Multimedia – 05 May 2024

Gene drive mosquitoes for malaria control

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Close up of Prof. Adoublaye Diabate giving a presentation

Media Coverage – 29 April 2024

How expensive it is to be poor Prof. Abdoulaye Diabaté inspires global action against malaria at TED2024

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Photo of Prof. Adboulaye Diabate speaking at TED

Press Release – 25 April 2024

How expensive it is to be poor: Prof. Abdoulaye Diabaté inspires global action against malaria at TED2024

...of genetic technologies, such as gene drive. www.targetmalaria.org Target Malaria receives core funding by the Bill & Melinda Gates Foundation and Open Philanthropy. The lead grantee organisation...

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A mosqito rests on a white fabric surface

Media Coverage – 25 April 2024

Soyons la génération qui met fin au paludisme

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A group of people holding up a blue mosquito net

Media Coverage – 25 April 2024

La lucha contra la malaria en África, en un punto crucial por la aprobación de dos vacunas

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Media Coverage – 25 April 2024

Embracing Inclusivity, Collaboration, And Equity To Accelerate Progress Towards A Malaria-Free World

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Prof Abdoulaye Diabate at the CBC Radio office

Media Coverage – 19 April 2024

The Current with Matt Galloway

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Media Coverage – 16 April 2024

Genetically modified mosquitoes could one day end malaria

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Abdoulaye Diabaté wearing a blue blazer. He has his arms crossed and has a serious expression.

Press Release – 12 April 2024

Africa’s Champion Against Malaria, Professor Abdoulaye Diabaté on stage at TED2024

...all areas of our work, creating a path for responsible research and development of genetic technologies, such as gene drive. www.targetmalaria.org Target Malaria receives core funding by the Bill &...

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Professor Abdoulaye Diabate

Media Coverage – 12 April 2024

Africa’s Champion Against Malaria, Professor Abdoulaye Diabaté on stage at TED2024

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Photo of Dr Lea Pare Toe

Media Coverage – 26 March 2024

Leading Female Researchers on a Mission to End Malaria

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A Target Malaria emplotee stands in a woodsy area, carrying out field work.

Blog – 12 February 2024

Our Work in Ghana 

...production proved to be an invaluable opportunity for skill development and knowledge sharing. https://www.youtube.com/watch?v=SiZiXz00XvA https://www.youtube.com/watch?v=4GOjf1YF1Z8 You can find “Our Work in Ghana” here on YouTube. Watch the video in Twi. ...

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Media Coverage – 12 February 2024

Could new vaccines end malaria in Africa?

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In Burkina Faso, A Target Malaria team member shows 3 women information on an a tablet. The women are sitting under a tree in front o a brick building.

Blog – 11 January 2024

Target Malaria’s stakeholder engagement approach 

...international organisations with interest in our work. We believe the communities knowledge, priorities and expectations help inform our research and ensure our technologies are effective and meet their needs.   https://www.youtube.com/watch?v=OVQvnTehOiI...

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Cover of the World Malaria Report 2023

Media Coverage – 03 January 2024

World Malaria Report 2023: A call for concerted action to address growing threats

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Figure: example of how a pathway to potential harm involving potential toxicity of gene drive mosquitoes has been rejeted because of our study

Blog – 14 November 2023

Assessment of the potential for toxicity and allergenicity from our gene drive mosquitoes 

...West Africa of our population suppression gene drive for malaria vector control, should they be approved, would not result in any increased allergenicity or toxicity in humans and animals.  ...

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Friends of the Global Fund Europe logo

Blog – 31 October 2023

Inclusive Health Systems: The Key to Addressing Global Health Challenges

...advocacy organization for global health and the fight against HIV, tuberculosis, and malaria. Its mission is to engage European decision-makers in investing and getting involved with the Global Fund: www.friendseurope.org. ...

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Prof Diabate on BF1TV

Media Coverage – 15 October 2023

Entretien au 7Infos du 15 octobre 2023 sur BF1TV avec le Prof. Abdoulaye Diabaté

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Professor Abdoulaye Diabate on BF1TV

Media Coverage – 08 October 2023

Entretien du 19H30 avec le Prof. Abdoulaye Diabaté

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Media Coverage – 29 September 2023

The Gamble: Can Genetically Modified Mosquitoes End Disease?

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Diabaté Abdoulaye observes a small cage in the lab

Press Release – 13 September 2023

Burkina Faso Professor Recognised as Falling Walls Winner in Science & Innovation Management 2023

...and Parasitology at Burkina Faso’s Research Institute in Health Sciences (Institut de recherche en sciences de la santé -IRSS), his work holds great promise in the fight against malaria transmission....

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Page – 29 August 2023

United Kingdom

In the United Kingdom, Target Malaria’s collaborating partners are Imperial College London and the University of Oxford, both consistently ranked among the world's top universities. Context of our work Imperial...

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World Mosquito Day August 20th 2023 #World Mosquito Day Join our #MosquitoCountdown Aug 1st - 20th

Blog – 04 August 2023

Why World Mosquito Day?

...no approved vaccine or specific treatment for chikungunya virus infections. Since 2004, outbreaks of CHIKV have become more frequent and widespread, caused partly due to viral adaptations allowing the virus...

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'Zero Malaria Starts With Me' Graphic. Celebrating 5 years of Zero Malaria Starts With Me. Let's end malaria for good.

Blog – 07 July 2023

Celebrating five years of Zero Malaria Starts with Me 

...action at all levels of society including among political, private sector and community leaders to accelerate malaria prevention and treatment and save lives. https://www.youtube.com/watch?v=fIGklXia7zI The RBM Partnership to End Malaria...

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A close-up of a sample dish that appears to have mosquito larvae on it

Media Coverage – 28 June 2023

How genetically modified mosquitoes could eradicate malaria

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Field entomologists kneel over a cloth, collecting mosquitos that have fallen onto it

Media Coverage – 21 June 2023

Utilizan mosquitos modificados genéticamente para combatir la malaria

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Page – 16 June 2023

Mozzie Drive Card Game

Mozzie Drive is an educational card game that demonstrates how gene drive technology could be used to reduce populations of malaria mosquitoes. This game was designed by Dr. Katie Willis...

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In a a lab, Krystal Birungi sits at a desk and looks into a microscope

Blog – 15 June 2023

My role as a malaria ambassador 

...personal experiences and advocating for the Fund’s work. This culminated in speaking at the Global Fund replenishment conference in 2022.  https://www.youtube.com/watch?v=-cXUzNgnXr4&ab_channel=TargetMalaria Speaking at the Global Fund Replenishment Conference Krystal with...

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Page – 25 May 2023

Uganda Virtual Press Kit

...Dr. Charles Mugoya Target Malaria: Uganda Factsheet Download PDF Our project brochure . Download PDF Photos & Videos © All rights reserved - Target Malaria Contact Target Malaria Uganda Contact...

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Page – 19 May 2023

Uganda

Target Malaria's team in Uganda works in collaboration with the Uganda Virus Research Institute (UVRI), based in Entebbe and is headed by Dr. Jonathan Kayondo. Context of our work Uganda...

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Page – 19 May 2023

Ghana

Target Malaria’s team in Ghana works in collaboration with the University of Ghana, Legon, based in Accra and is headed by Dr. Fred Aboagye-Antwi. Context of our work Malaria is...

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Two scientist stand in a lab, they look towards a white board with information on it.

Media Coverage – 18 May 2023

Entretien Canal+ avec Professeur Abdoulaye Diabaté et Dr. Lea Pare Toe

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Page – 16 May 2023

Burkina Faso

Target Malaria’s team in Burkina Faso works in collaboration with the Institut de Recherche en Sciences de la Santé (IRSS), based in Bobo-Dioulasso and is headed by Professor Abdoulaye Diabaté....

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Louise Marston looks at a small cage filled with mosquitos

Media Coverage – 25 April 2023

‘The new rock n roll stars of our time’: Photographer Rankin swaps celebrities for scientists

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A close up of a scientist inserting a syringe into a small container.

Media Coverage – 25 April 2023

Paludisme: les innovations face aux résistances du parasite

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Media Coverage – 24 April 2023

A new malaria vaccine could be a ‘huge deal’ in the fight to save lives in Africa and abroad

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Media Coverage – 23 April 2023

Kampf gegen Malaria geht in die nächste Runde

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Screenshot of a webpage featuring a radio show titled 'The Current with Matt Galloway'. Subheading reads: 'Vaccine could be a game changer in the fight against malaria'.

Media Coverage – 21 April 2023

The Current with Matt Galloway

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Blog – 24 March 2023

How do communities the project engages with make informed decisions about our work?

I’m pleased to share a new animation video which explains how communities the project engages with make informed decisions about our work. https://www.youtube.com/watch?v=N1ldtoJMZ3Y&t=22s Stakeholder engagement is at the core of...

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Page – 17 March 2023

Community Engagement

In the villages and around our insectaries, we use culturally appropriate communication tools that are co-developed by the communities and the teams in local languages taking into consideration stakeholders’ preferences....

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Blog – 17 March 2023

Reintroducing where we work 

...laboratory was recently inaugurated at the University of Ghana to facilitate some of the planned research. The insectary will not be working with genetically modified mosquitoes.   https://www.youtube.com/watch?v=oEwrtVADfxM&list=PL4j19OrfcF4zyaiGh7YeTM1u2iXChA8-T&index=2&ab_channel=iBOLConsortium The team in...

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Spokeperson – 02 March 2023

Dr. Patric Epopa

Dr. Patric Stephane Epopa is the field entomology coordinator for Target Malaria Burkina Faso at the Research Institute in Health Sciences (Institut de Recherche en Science de la Santé (IRSS)...

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Media Coverage – 01 March 2023

Mosquito ecology research facility inaugurated

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Publication – 24 February 2023

Engagement on risk assessment for gene drive mosquitoes by EFSA and Target Malaria

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Spokeperson – 24 February 2023

Dr. Martin Lukindu

Martin Lukindu is a post-doctoral research associate for Target Malaria in Uganda. Martin joined Target Malaria in 2013 as a field entomology coordinator, and left in 2015 for his doctoral...

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Page – 07 February 2023

Photos & Videos

Photos © All rights reserved - Target Malaria Videos...

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Spokeperson – 02 February 2023

Dr. Alexandre Quach

Alexandre Quach is Stakeholder Engagement Officer for Target Malaria, based at Imperial College, UK.  Since 2022, Alex has been providing support to Stakeholder Engagement teams involved in the project, contributing to...

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Spokeperson – 31 January 2023

Dr. Charles Guissou

Dr. Charles Guissou is a public health physician. He received his Medical Doctor degree in Medicine at the University of Ouagadougou in Burkina Faso in 2009 and a master’s degree...

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Photo of Dr. Talya Hackett 

Spokeperson – 31 January 2023

Dr. Talya D. Hackett

Dr. Talya D. Hackett, based at the Department of Biology at the University of Oxford, researches the potential ecological consequences of supressing Anopheles gambiae populations at Target Malaria. Talya’s work...

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Spokeperson – 31 January 2023

Dr. Samantha O’Loughlin

Dr Samantha O’Loughlin is a population geneticist and stakeholder engagement support officer for Target Malaria at Imperial College London. In 2006, she took on a post-doctoral research position in a...

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Spokeperson – 31 January 2023

Naima Sykes

Naima Sykes is a strategic communications and stakeholder engagement specialist working with an excellent global team to manage one of Target Malaria’s three pillars – Stakeholder Engagement. Her role is...

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Spokeperson – 31 January 2023

Dr. Lea Pare Toe

Dr. Lea Pare Toe is the Stakeholder Engagement Lead for Target Malaria Burkina Faso, which is part of the Target Malaria consortium based at the Institut de Recherches en Sciences...

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Spokeperson – 31 January 2023

Krystal Mwesiga Birungi

Krystal Mwesiga Birungi is the Field Entomology Coordinator for Target Malaria Uganda which is part of the Target Malaria consortium and based at the Uganda Virus Research Institute. For the...

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Spokeperson – 31 January 2023

Jude Thaddeus Bigirwenkya

Jude Thaddeus Bigirwenkya is a Stakeholder Engagement Manager for Target Malaria in Uganda. Joining in 2020, Jude has worked to expand the reach to different stakeholders from the community level...

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Spokeperson – 31 January 2023

Dr. Jonathan Kayondo

Dr. Jonathan Kayondo is Principal Investigator for Target Malaria in Uganda. He is also Senior Research Officer for the Department of Entomology, and the current acting Head of the Department...

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Spokeperson – 31 January 2023

Dr. John B. Connolly

Dr. John B. Connolly is the Senior Regulatory Science Officer for Target Malaria. He joined Target Malaria at Imperial College London in 2017 and is the Senior Regulatory Science Officer...

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Spokeperson – 30 January 2023

Dr. Fred Aboagye-Antwi

Dr. Fred Aboagye-Antwi is Principal Investigator for Target Malaria in Ghana. He is also a Medical Entomologists at the Department of Animal Biology & Conservation Sciences and a Senior Lecturer...

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Spokeperson – 30 January 2023

Dr. Federica Bernardini

Dr. Federica Bernardini is a Research Associate at Imperial College London, working on novel strategies to control the mosquito vector of human malaria. Since the start of their PhD studies...

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Spokeperson – 30 January 2023

Dr. Charles Mugoya

Dr. Charles Mugoya is Regulatory Affairs Manager for Africa at Target Malaria. Dr. Mugoya is an entomologist by training. He started his working career with ICIPE as Resident Scientist in...

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Dr. Alekos Simoni

Spokeperson – 30 January 2023

Dr. Alekos Simoni

Dr. Alekos Simoni is a molecular biologist specialising in gene drive and mosquito research. He is currently serving as technical support specialist for Target Malaria UK at Imperial College London. ...

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Blog – 27 January 2023

Reflections on 2022

...modified line.iii  Target Malaria Burkina Faso team with the shipment of eggs You can watch the team receive the shipment below: https://www.youtube.com/watch?v=HsZpMRwEjxM&ab_channel=TargetMalaria Ghana continued their ecological observatory studies and completed...

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Professor Abdoulaye Diabate

Spokeperson – 27 January 2023

Prof. Abdoulaye Diabaté

...TED Talk was on “How to end malaria once and for all” and focused on the potential of gene drive technology to genetically modify mosquitoes and control malaria in Africa. https://www.ted.com/talks/abdoulaye_diabate_how_to_end_malaria_once_and_for_all?subtitle=en...

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Page – 26 January 2023

Insectary activities

Insectary activities are at the heart of Target Malaria’s R&D program with a remit for creation, evaluation, maintenance and production for field evaluation of genetically modified mosquitoes for malaria control....

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Page – 19 January 2023

Genetically Modified Male Bias

Non Gene Drive Following development of the non gene drive sterile male, the Target Malaria team developed a genetically modified Anopheles gambiae mosquito that could successfully mate and produce offspring,...

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News – 18 January 2023

“Swarm” – a sonification of the 2016 cage trials by Imperial College London

...hatching sound at the beginning of each generation (every 7 days) RFP+ % (gene modification rate) Synth Harmonic (pitch rises as gene modification increases) instagram: jamie_perera twitter: @jamiepereramuso linkedin: https://www.linkedin.com/in/jamieperera/...

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Publication – 13 January 2023

Effects of storage conditions and digestion time on DNA amplification of biting midge (Culicoides) blood meals

Ben Bellekom, Abigail Bailey, Marion England, Zoe Langlands, Owen T. Lewis, Talya D. Hackett. Effects of storage conditions and digestion time on DNA amplification of biting midge (Culicoides) blood meals....

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Blog – 14 December 2022

African leaders prioritise health at the Global Fund replenishment

...many people now as they did 20 years ago according to Global Fund. Thanks to the Replenishment outcome, the Board approved ambitious investments totaling US$13.6 billion, including US$518 million for...

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Page – 12 December 2022

Why Malaria Matters

Every year, malaria kills over 608 000 people and infects over 249 million people; a third of the world is at risk of contracting this disease transmitted by mosquitoes. The...

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Publication – 24 November 2022

Analysis of the Genetic Variation of the Fruitless Gene within the Anopheles gambiae (Diptera: Culicidae) Complex Populations in Africa

Mahamadi Kientega, Nace Kranjc, Nouhoun Traoré, Honorine Kaboré, Dieudonné Diloma Soma, Ioanna Morianou, Moussa Namountougou, Adrien Marie Gaston Belem, Abdoulaye Diabate. Analysis of the Genetic Variation of the Fruitless Gene...

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Blog – 16 November 2022

How Earth Observation Data is used by Target Malaria

...of geographical variables on the dynamics of vectors and diseases. At Target Malaria, we use various sources of earth observation data such as: Free online imagery resources: Google Earth; ESRI;...

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Media Coverage – 30 October 2022

Why African scientists are supporting gene drive research to fight malaria

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Media Coverage – 20 October 2022

Target Malaria’s scientists are working to rid Africa of an ancient plague

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Publication – 16 October 2022

Driving down malaria transmission with engineered gene drives

Garrood WT, Cuber P, Willis K, Bernardini F, Page NM, Haghighat-Khah RE. Driving down malaria transmission with engineered gene drives. Front Genet. 2022 Oct 19;13:891218. doi: 10.3389/fgene.2022.891218

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Publication – 16 October 2022

Introgression of a synthetic sex ratio distortion transgene into different genetic backgrounds of Anopheles coluzzii

 Pollegioni P, Persampieri T, Minuz RL, Bucci A, Trusso A, Di Martino S, Leo C, Bruttini M, Ciolfi M, Waldvogel AM, Tripet F, Simoni A, Crisanti A, Müller R....

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Publication – 16 October 2022

Points to consider in seeking biosafety approval for research, testing, and environmental release of experimental genetically modified biocontrol products during research and development

Tonui WK, Ahuja V, Beech CJ, Connolly JB, Dass B, Glandorf DCM, James S, Muchiri JN, Mugoya CF, Okoree EA, Quemada H, Romeis J. Points to consider in seeking biosafety...

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Page – 03 October 2022

Home

Malaria fights hard. We fight harder. The Zero Malaria Experience shows how innovation and funding can save lives and end malaria. Discover more Episode 5: Can we outsmart disease? Target...

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Media Coverage – 21 September 2022

Importance of Risk Assessment in Science

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Publication – 16 September 2022

Transgenic Insects: Techniques and Applications (2nd Edition)

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Publication – 23 August 2022

A theory of resistance to multiplexed gene drive demonstrates the significant role of weakly deleterious natural genetic variation

Khatri BS, Burt A. A theory of resistance to multiplexed gene drive demonstrates the significant role of weakly deleterious natural genetic variation. Proc Natl Acad Sci U S A. 2022...

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DW Headline Titled 'Wiping out mosquitos'

Media Coverage – 12 August 2022

We could kill all mosquitoes (but should we?)

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Publication – 01 July 2022

Gene drive in species complexes: defining target organisms

John B. Connolly, Jörg Romeis, Yann Devos, Debora C.M. Glandorf, Geoff Turner, Mamadou B. Coulibaly, Gene drive in species complexes: defining target organisms, Trends in Biotechnology, 2022, ISSN 0167-7799, https://doi.org/10.1016/j.tibtech.2022.06.013....

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Publication – 01 July 2022

Comprehensive characterization of a transgene insertion in a highly repetitive, centromeric region of Anopheles mosquitoes

Matteo Vitale, Chiara Leo, Thomas Courty, Nace Kranjc, John B. Connolly, Giulia Morselli, Christopher Bamikole, Roya Elaine Haghighat-Khah, Federica Bernardini & Silke Fuchs (2022) Comprehensive characterization of a transgene insertion...

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Blog – 15 June 2022

How to advance environmental risk assessment of gene drive for malaria when it’s never been done before

...Malaria experts and 11 external experts from multiple disciplines. The report’s nine recommendations are the result of six online workshops involving 50 experts from four continents who were invited to...

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Media Coverage – 03 June 2022

Who decides whether to use gene drives against malaria-carrying mosquitoes?

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Media Coverage – 23 May 2022

The sci-fi technology tackling malarial mosquitos

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Blog – 11 May 2022

Importation of the non gene drive genetically modified male bias mosquito strain into Burkina Faso

...import and conduct contained use studies on the male bias strain. It follows the three years of successful work on the non gene drive genetically modified sterile male mosquitoes. https://www.youtube.com/watch?v=HsZpMRwEjxM&t=8s&ab_channel=TargetMalaria...

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A woman holds up two small jars

Media Coverage – 23 April 2022

Kampf gegen Malaria geht in die nächste Runde

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News – 12 April 2022

Fight for What Counts: The Global Fund’s Seventh Replenishment

...closer to ending malaria. Now is the moment to fight for what counts and protect everyone, everywhere from the deadliest infectious diseases and build a healthier, more equitable world. https://www.youtube.com/watch?v=2BBEgoxm8wY&feature=emb_logo...

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Publication – 06 April 2022

A multi-disciplinary approach for a building common understanding of genetic engineering for malaria control in Burkina Faso

https://www.nature.com/articles/s41599-022-01122-7 A multi-disciplinary approach for a building common understanding of genetic engineering for malaria control in Burkina Faso...

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Publication – 01 April 2022

Life-history attributes of juvenile Anopheles gambiae s.s. in central Uganda; implications for malaria control interventions

Batume, C., Akol, A.M., Mukwaya, L.G., Birungi, J. & Kayondo, J.K. (2022) Life-history attributes of juvenile Anopheles gambiae s.s. in central Uganda; implications for malaria control interventions. Medical and Veterinary...

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Blog – 17 March 2022

Meet the people at Target Malaria helping #BreakTheBias this International Women’s Day

...innovation is essential to stay ahead of the malaria parasite and mosquito, and Target Malaria is proud to be contributing towards these efforts. https://www.youtube.com/watch?v=ECYI6jLYHAY We would like to warmly thank...

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Photo of a rural village

Multimedia – 22 February 2022

People Fixing the World: The house that fights malaria

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Blog – 10 February 2022

Entomological results from the first release of non gene drive genetically modified sterile male mosquitoes in Africa

...mosquito that is genetically modified to be sterile, so it can mate but cannot produce offspring. It does not carry the gene drive technology. https://www.youtube.com/watch?v=H7i9Anh0_Dg&ab_channel=TED-Ed The sterile male mosquitoes reared...

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Publication – 10 February 2022

Mark-release-recapture experiment in Burkina Faso demonstrates reduced fitness and dispersal of genetically-modified sterile malaria mosquitoes

Mark-release-recapture experiment in Burkina Faso demonstrates reduced fitness and dispersal of genetically-modified sterile malaria mosquitoes

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Media Coverage – 08 February 2022

GFAN Speakers Bureau Shorts – Krystal

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News – 25 January 2022

New office building for the Target Malaria Mali team

...and Pharmacy. Target Malaria has partnered with the MRTC since 2012, and this new office represents the strong links between the institution and Target Malaria team, helping to provide a...

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Publication – 12 January 2022

Preparing an Insectary in Burkina Faso to Support Research in Genetic Technologies for Malaria Control

Preparing an Insectary in Burkina Faso to Support Research in Genetic Technologies for Malaria Control

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Publication – 12 January 2022

Local adaptation and colonization are potential factors affecting sexual competitiveness and mating choice in Anopheles coluzzii populations

Local adaptation and colonization are potential factors affecting sexual competitiveness and mating choice in Anopheles coluzzii populations

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Blog – 11 January 2022

Reflections on 2021

...and inbreeding at low density. (Preprint) https://www.biorxiv.org/content/10.1101/2021.11.11.468225v2. [9] Bhavin S. Khatri BS, Burt A. Weakly deleterious natural genetic variation amplifies probability of resistance in multiplexed gene drive systems (Pre-print) https://www.biorxiv.org/content/10.1101/2021.12.23.473701v2....

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Publication – 06 December 2021

WHO World malaria report 2021

World malaria report 2021

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Publication – 04 December 2021

The Potential for a Released Autosomal X-Shredder Becoming a Driving-Y Chromosome and Invasively Suppressing Wild Populations of Malaria Mosquitoes

Alcalay Y, Fuchs S, Galizi R, Bernardini F, Haghighat-Khah RE, Rusch DB, Adrion JR, Hahn MW, Tortosa P, Rotenberry R, Papathanos PA. The Potential for a Released Autosomal X-Shredder Becoming...

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Blog – 02 December 2021

Arthropod Containment Guidelines updated with addendum on gene drive

...and safety, to animal and plant health, or to animal or plant products. 7CFR Part 331, 9 CFR Part 121, and 42 CFR Part 73 For more information visit: https://www.cdc.gov/cpr/dsat/what-is-select-agents.htm...

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Blog – 12 October 2021

WHO recommends malaria vaccine for broad-scale use in Africa

...specific and diverse needs of different communities and geographies at risk of malaria. https://www.youtube.com/watch?v=PfJnB2hPCWk&t=395s Dr Andrew Hammond, Imperial College London, discusses vaccines and the use of gene drive technology for...

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Publication – 04 September 2021

A systematic review assessing the potential for release of vector species from competition following insecticide-based population suppression of Anopheles species in Africa

Qureshi A, Connolly JB. A systematic review assessing the potential for release of vector species from competition following insecticide-based population suppression of Anopheles species in Africa. Parasit Vectors. 2021 Sep...

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News – 20 August 2021

World Mosquito Day: Understanding the malaria vector

...safe and approved. A reduction in female Anopheles mosquito numbers will lead to a reduction in malaria transmission.  Malaria is an infectious disease with a huge impact on the economic...

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Large, white, floor-to-ceiling mosquito cages at Polo GGB

Media Coverage – 28 July 2021

Malarial mosquitoes suppressed in experiments that mimic natural environments

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Photo of a mosquito against a white background

Media Coverage – 28 July 2021

Genetic engineering test with mosquitoes ‘may be game changer’ in eliminating malaria

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News – 15 July 2021

Convention on Biological Diversity talks go virtual

Throughout most of May and June we followed an online meeting that will have important consequences for the natural world, yet is largely overlooked by the general public and even...

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Publication – 04 July 2021

Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field

Hammond A, Pollegioni P, Persampieri T, North A, Minuz R, Trusso A, Bucci A, Kyrou K, Morianou I, Simoni A, Nolan T, Müller R, Crisanti A. Gene-drive suppression of mosquito...

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Publication – 02 July 2021

Global Malaria Burden Map by Medicines for Malaria Venture (MMV) and the WHO Global Malaria Programme

https://www.severemalaria.org/severe-malaria/global-malaria-burden-map

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Blog – 30 June 2021

Talking public health, biodiversity and development at the European Development Days

The European Development Days (EDD), Europe’s leading forum for international cooperation and development, took place from June 15-16, 2021. The virtual event was equipped with an online platform designed to...

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News – 16 June 2021

WHO releases updated Guidance framework for testing of genetically modified mosquitoes

...gene drive genetically modified mosquitoes (GMM) have been approved and released in specific field applications (some at commercial scale) in South America, North America and Africa; next generation improvements in...

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Blog – 09 June 2021

Laying the groundwork for a community agreement framework for gene drive research in Africa

...of gene drive mosquitoes would have to be approved by the community as a group before it could be allowed to take place.   While there is ample guidance in...

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Publication – 02 June 2021

A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression

Chrysanthi Taxiarchi  ...

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Photo of the electric lock beside a door at the Burkina Faso Lab entrance

Media Coverage – 20 May 2021

Burkina Faso Testing Genetically Modified Mosquitoes to Curb Malaria

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Publication – 19 May 2021

WHO issues new guidance for research on genetically modified mosquitoes to fight malaria and other vector-borne diseases

WHO issues new guidance for research on genetically modified mosquitoes to fight malaria and other vector-borne diseases

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Blog – 19 May 2021

Disparities in malaria risk and resilience amongst rural populations in western Burkina Faso

...Lassane Yameogo, of the Université Joseph KI- Zerbo in Ouagadougou, Burkina Faso. The aim of my research project was to analyse the resilience of rural populations in western Burkina Faso...

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Publication – 04 May 2021

Genetic Technologies for Sustainable Management of Insect Pests and Disease Vectors

Silvia Grilli, Roberto Galizi and Chrysanthi Taxiarchi. G Genetic Technologies for Sustainable Management of Insect Pests and Disease Vectors. Sustainability 2021, 13(10), 5653...

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Publication – 04 May 2021

Contemporary Ne estimation using temporally spaced data with linked loci

Hui TJ, Brenas JH, Burt A. Contemporary Ne estimation using temporally spaced data with linked loci. Mol Ecol Resour. 2021 Oct;21(7):2221-2230.

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News – 25 April 2021

Target Malaria’s Young Scientists Draw the Line Against Malaria on World Malaria Day

...campaign’s short film where she plays a school teacher. She tells us more about it in this blog’s post. https://www.youtube.com/watch?v=o3Elc08Zo4o&ab_channel=TargetMalaria Every two minutes, a child dies from malaria. This is...

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Publication – 01 April 2021

Analysis of off-target effects in CRISPR-based gene drives in the human malaria mosquito

Garrood WT, Kranjc N, Petri K, Kim DY, Guo JA, Hammond AM, Morianou I, Pattanayak V, Joung JK, Crisanti A, Simoni A. Analysis of off-target effects in CRISPR-based gene drives...

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Media Coverage – 05 March 2021

In Uganda, genetically modified mosquitoes bring hope and fear

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Publication – 01 March 2021

Proceedings of an expert workshop on community agreement for gene drive research in Africa – Co-organised by KEMRI, PAMCA and Target Malaria

...workshop on community agreement for gene drive research in Africa – Co-organised by KEMRI, PAMCA and Target Malaria [version 2; peer review: 2 approved]. Gates Open Res 2021, 5:19 (https://doi.org/10.12688/gatesopenres.13221.2)...

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Photo of Dr. Keri Harp

News – 01 March 2021

New parasitologist

...not in the labs, you can find me rafting or hiking with my husband and three dogs – a husky mix, and two Great Danes. Follow me on LinkedIn: https://www.linkedin.com/in/kerioxendineharp/...

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Blog – 10 February 2021

Using DNA barcodes in the fight against malaria

...https://www.youtube.com/watch?v=oEwrtVADfxM With this objective in mind, researchers at the University of Ghana have been collecting data on the ground that will eventually lead to the creation of an “ecological network”,...

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Blog – 03 February 2021

Making Target Malaria’s science accessible to kids

...messages, emphasising the need to remove standing water, use bednets, have window screens, and apply approved insecticides and repellents.  Personally, it is rewarding to think that Tilly, Ellen and myself...

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Publication – 22 December 2020

We need to redefine the relationship between science and its end-users

We need to redefine the relationship between science and its end-users by Léa Parre-Toe...

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Publication – 11 December 2020

WHO World malaria report 2020

WHO World malaria report 2020

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Spokeperson – 24 November 2020

Dr. Mamadou Coulibaly

...Target Malaria Mali. With an early interest and a keen intellectual curiosity for science, Dr. Mamadou Coulibaly obtained his doctorate degree in Pharmacy in 1999 in his home country of...

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Multimedia – 05 November 2020

Brave New Planet: Episode 6: Reshaping Nature Through Gene Drives

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DNA Illustration

Media Coverage – 28 October 2020

Interview with Professor Austin Burt: Role of gene drive technology in the context of the EU’s Biodiversity Strategy 2030

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Blog – 22 October 2020

Why eradicating Malaria in Africa requires a specific approach and new tools?

...et al. (2020) Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: a modelling study. Lancet Glob Health; published online July 13. https://doi.org/10.1016/S2214-109X(20)30317-X...

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Blog – 15 October 2020

Investment in new vector control tools recommended if we are to avoid malaria resurgence, new study indicates

...C, Jensen HT (2020) Will More of the Same Achieve Malaria Elimination? Results from an Integrated Macroeconomic Epidemiological Demographic Model. Am J Trop Med Hyg.; published online September 21. https://doi.org/10.4269/ajtmh.19-0472...

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Publication – 15 October 2020

Cellular mechanisms regulating synthetic sex ratio distortion in the Anopheles gambiae germline

Haghighat-Khah RE, Sharma A, Wunderlich MR, Morselli G, Marston LA, Bamikole C, Hall A, Kranjc N, Taxiarchi C, Sharakhov I, Galizi R. Cellular mechanisms regulating synthetic sex ratio distortion in...

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Publication – 03 September 2020

European Academies’ Science Advisory Council report on Genome Editing

European Academies’ Science Advisory Council report on Genome Editing  ...

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Publication – 03 September 2020

The OECD Working Party on Biotechnology, Nanotechnology and Converging Technologies (BNCT) published a report entitled “Gene editing in an international context: Scientific, economic and social issues across sectors”

The OECD Working Party on Biotechnology, Nanotechnology and Converging Technologies (BNCT) published a report entitled “Gene editing in an international context: Scientific, economic and social issues across sectors”  ...

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Publication – 03 September 2020

International experts report on the “Pathway to Deployment of Gene Drive Mosquitoes as a Potential Biocontrol Tool for Elimination of Malaria in Sub-Saharan Africa: Recommendations of a Scientific Working Group”

   ...

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Blog – 25 August 2020

Understanding the population dynamics of a self-limiting male bias strain in malaria mosquitoes

...is making important scientific advances in the development of self-limiting strategies for vector control for malaria. More details about these experiments are available in the Journal of Applied Ecology. https://besjournals.onlinelibrary.wiley.com/doi/full/10.1111/1365-2664.13702?af=R...

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Publication – 20 August 2020

Modelling the suppression of a malaria vector using a CRISPR-Cas9 gene drive to reduce female fertility

North A, Burt A, Godfray HCJ. Modelling the suppression of a malaria vector using a CRISPR-Cas9 gene-drive to reduce female fertility. BMC Biol. 2020 Aug 11;18(1):98. doi: 10.1186/s12915-020-00834-z.

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Blog – 20 August 2020

Virtual tours of Target Malaria’s insectaries to celebrate World Mosquito Day

...process for import and release in Africa. Institut de Recherche en Science de la Santé (Burkina Faso) and the Malaria Research and Training Center (Mali) https://www.youtube.com/watch?v=-GNqWOq024Q The teams in Burkina...

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Blog – 11 August 2020

Malaria, tuberculosis, and HIV : how can the impact of COVID-19 be minimised

...al. (2020) Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: a modelling study. Lancet Glob Health; published online July 13. https://doi.org/10.1016/S2214-109X(20)30317-X [2]...

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Blog – 24 July 2020

Bridging the investment gap in the fight against malaria

...external funding for malaria initiatives accounting for 65% of all international financing for malaria, and has invested more than US$12.5 billion in malaria control programs as at December 2019, https://www.theglobalfund.org/en/malaria/...

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Publication – 20 July 2020

Providing a policy framework for responsible gene drive research: an analysis of the existing governance landscape and priority areas for further research

...framework for responsible gene drive research: an analysis of the existing governance landscape and priority areas for further research. Wellcome Open Res. 2020; 5: 173. Published online 2020 Jul 20....

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Blog – 29 June 2020

Crisanti lab on lockdown

...online working platforms.   Egg shipment mission  In order to pursue some important experiments with collaborators in Italy, the team was involved in the shipment of four mosquito strains. Each group...

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Page – 26 June 2020

How gene drive works

Currently, we are evaluating a number of approaches to reduce the number of malaria mosquitoes using genetic modification, in particular gene drive technologies. This work is still at an early...

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Publication – 20 June 2020

Detecting the population dynamics of an autosomal sex-ratio distorter in a malaria vector

Pollegioni P, North A, Persampieri T, Bucci A, Minuz R, Groneberg DA, Nolan T, Papathanos P, Crisanti A, Muller R. Detecting the population dynamics of an autosomal sex-ratio distorter in...

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Page – 11 June 2020

Where We Operate

Malaria is present in many regions of the world, with the greatest burden in sub-Saharan Africa. This area is where around 95% of all malaria-related deaths occur, and where domestic...

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Page – 02 June 2020

Privacy Policy

...visit(s), your computer or mobile device’s Internet Protocol (IP) address How is your personal information collected? The following information is collected if you complete our online form: Your name The...

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Publication – 20 May 2020

A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae

Simoni A, Hammond AM, Beaghton AK, Galizi R, Taxiarchi C, Kyrou K, Meacci D, Gribble M, Morselli G, Burt A, Nolan T, Crisanti A. A male-biased sex distorter gene drive...

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Blog – 11 May 2020

Target Malaria scientists create a genetically modified mosquito to produce male-only progeny that effectively reduces the population of malaria mosquitoes in the lab at Imperial College

...We hope to resume our activities soon. ‘A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae’ is now available at the journal Nature Biotechnology. Read more: www.pologgb.com...

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Publication – 20 April 2020

Auditing Preparedness for Vector Control Field Studies

Collins CM, Quinlan MM. Auditing Preparedness for vector control field studies. Am J Trop Med Hyg. 2020 Apr;102(4):707-710. doi:10.4269/ajtmh.19-0710

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Publication – 20 April 2020

The development of complex and controversial innovations. Genetically modified mosquitoes for malaria eradication

Cisnetto V, Barlow J. The development of complex and controversial innovations. Genetically modified mosquitoes for malaria control. Res Policy. 2020 Apr;49(3):103917. doi: 10.1016/j.respol.2019.103917.

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Blog – 27 March 2020

COVID-19: We are here for you

...some of the best practices that we all should be following. https://www.youtube.com/watch?v=F_0T0A9mAsc&t=3s Like malaria, let’s fight to prevent the spread of COVID-19 together. Stay safe, stay well, take good care....

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Blog – 09 March 2020

My Interview on Target Malaria in Italian

...NOTA BENE: Both links are about the whole podcast (more than 1h), my interview is after 6mins from the start (and it lasts around 15mn). Youtube link https://www.youtube.com/watch?v=240tVd1aES0 Spreaker link https://www.spreaker.com/user/scientificast/scientificast289...

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Blog – 08 January 2020

Dr Mamadou Coulibaly

...in Mali. With an early interest and a keen intellectual curiosity for science, Dr. Mamadou Coulibaly obtained his doctorate degree in Pharmacy in 1999 in his home country of Mali....

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Publication – 14 December 2019

WHO World Malaria Report 2019

World Malaria Report 2019

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Media Coverage – 24 July 2019

Des moustiques génétiquement modifiés lâchés dans la nature

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Media Coverage – 05 July 2019

Au Burkina, un premier lâcher de moustiques génétiquement modifiés crée la polémique

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Publication – 20 April 2019

Knowledge engagement in gene drive research for malaria control

Sarah Hartley, Delphine Thizy, Katie Ledingham, Mamadou Coulibaly, Abdoulaye Diabaté, Bakara Dicko, Samba Diop, Jonathan Kayondo, Annet Namukwaya, Barry Nourou, Léa Paré Toé. Knowledge engagement in gene drive research for...

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Publication – 20 April 2019

Guidance on stakeholder engagement practices to inform the development of area-wide vector control methods

Delphine Thizy, Claudia Emerson, Johanna Gibbs, Sarah Hartley, Lydia Kapiriri, James Lavery, Jeantine Lunshof, Janine Ramsey, Julie Shapiro, Jerome Amir Singh, Lea Pare Toe, Isabelle Coche, Benjamin Robinson. Guidance on...

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Publication – 20 April 2019

Sustainable innovation in vector control requires strong partnerships with communities

Frederic Bartumeus, Guilherme B. Costa, Roger Eritja, Ann H. Kelly, Marceline Finda, Javier Lezaun, Fredros Okumu, M. Megan Quinlan, Delphine C. Thizy, Léa Paré Toé, Megan Vaughan. Sustainable innovation in...

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A man speaks at a podium with a Wired Health logo on it. Behind him is a large screen displaying a presentation, and the words "Health." and "WIRED" are prominently visible. The setting appears to be a professional conference or event dedicated to health topics.

Multimedia – 10 April 2019

How genetically-modified mosquitoes could eradicate Malaria

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Media Coverage – 10 April 2019

Austin Burt: How genetically-modified mosquitoes could eradicate Malaria

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Publication – 14 December 2018

WHO World Malaria Report 2018

World Malaria Report 2018...

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Blog – 04 December 2018

Feedback on the Convention on Biological Diversity

...interest groups. The discussion highlighted the potential benefits of these technologies as well as the request responsible research.   On 29th, the final text was approved by the parties. It...

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Blog – 23 November 2018

Burkina Faso is getting ready for its next stage of research – sterile male mosquito release

...the video below to learn more about our stakeholder engagement work with local participant in the neighbourhood of the Institut de Recherche en Sciences de la Santé in Bobo-Dioulasso. https://www.youtube.com/watch?v=ZuhVLw5LEQI...

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Illustration of a mosquito and a test tube containing DNA

Media Coverage – 08 November 2018

The promise and peril of gene drives

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Media Coverage – 19 October 2018

Why is this African village letting mosquitoes in?

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Snapshot from a TedX YouTube Video, displaying an illustration of a red mosquito with a target on it, and the words "GENE DRIVE" written above it. Featuring a background illustration of a DNA strand.

Media Coverage – 26 September 2018

A genetically modified organism could end malaria and save millions of lives — if we decide to use it

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Publication – 03 September 2018

The African Union’s report on “Gene Drives for malaria control and elimination in Africa”

The African Union’s report on “Gene Drives for malaria control and elimination in Africa”  ...

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Publication – 20 July 2018

Effects of the removal or reduction in density of the malaria mosquito, Anopheles gambiae s.l., on interacting predators and competitors in local ecosystems

Collins, C.M., Bonds, J.A.S., Quinlan, M.M., Mumford, J.D. (2018) . Effects of the removal or reduction in density of the malaria mosquito, Anopheles gambiae s.l., on interacting predators and competitors...

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Blog – 06 July 2018

Our stakeholder engagement approach in Uganda

...approved by the Ugandan Virus Research Institute’s ethics committee and by the Ugandan National Council for Science and Technology. Our engagements activities have mainly been focused on the communities in...

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Publication – 14 June 2018

Pathway to Deployment of Gene Drive Mosquitoes as a Potential Biocontrol Tool for Elimination of Malaria in Sub-Saharan Africa: Recommendations of a Scientific Working Group

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Publication – 04 June 2018

Report of the High-Level African Union Panel on Emerging Technologies (APET) on Gene Drives for Malaria Control and Elimination in Africa

Report of the High-Level African Union Panel on Emerging Technologies (APET) on Gene Drives for Malaria Control and Elimination in Africa. Available in French and in English

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Publication – 04 March 2018

Gene editing in an international context: Scientific, economic and social issues across sectors by OECD

Gene editing in an international context: Scientific, economic and social issues across sectors by OECD

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Publication – 20 December 2017

Gene drive to reduce malaria transmission in sub-Saharan Africa

Austin Burt, Mamadou Coulibaly, Andrea Crisanti, Abdoulaye Diabate & Jonathan K. Kayondo (2018) Gene drive to reduce malaria transmission in sub-Saharan Africa, Journal of Responsible Innovation, 5:sup1, S66-S80, DOI: 10.1080/23299460.2017.1419410...

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Blog – 07 December 2017

Imperial academic puts community at the heart of malaria elimination project

Professor Austin Burt has been awarded a President’s Medal for his work engaging the public in malaria-control projects across sub-Saharan Africa....

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Blog – 07 December 2017

Channel 4, Fight against malaria has stalled, World Health Organisation says

Progress in the fight against Malaria has stalled, the World Health Organisation warned this week.

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Blog – 07 December 2017

Nature, Genetic engineering: On the road to efficient gene drives

Containment of malaria transmission largely depends on vector control — that is, on eliminating the parasite-transmitting Anopheles mosquito — and gene drives have emerged as a promising approach to achieve...

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Blog – 07 December 2017

Can Scientists Convince the Public to Accept CRISPR and Gene Drives?

Scientists are trying new ways to win over a skeptical public

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Blog – 07 December 2017

Outwitting nature’s greatest killer

Scientists deploy new weapons to eradicate an age-old enemy: Mosquitoes

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Publication – 03 December 2017

World Malaria Report 2017

World Malaria Report 2017  ...

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Blog – 16 June 2017

Dr. Abdoulaye Diabaté give us an insight into Target Malaria’s team work in Burkina Faso

...then submitted an application of importation to the NAB which was approved after a thorough evaluation and review of the dossier. Alongside the renovations and submission, the team in country...

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Blog – 10 May 2017

SciDev, GM drive against malaria: Treading a fine line, April 2017

An international group of scientists is pushing a groundbreaking DNA editing programme known as “mosquito gene drive” for a long-term solution to the spread of malaria in Africa.

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Blog – 10 May 2017

Stat News, In a remote West African village, a revolutionary genetic experiment is on its way — if residents agree to it, March 2017

BANA, Burkina Faso — This small village of mud-brick homes in West Africa might seem the least likely place for an experiment at the frontier of biology.

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Blog – 10 May 2017

Wired, Illustrated experiment: modifying mosquitoes to save millions of lives, March 2017

Malaria, a disease transmitted by a type of mosquito called Anopheles, kills 500,000 people every year, most of them in Africa. But Andrea Crisanti, professor of molecular parasitology at London’s...

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Blog – 10 May 2017

The Scientist , Using gene drive to limit the spread of malaria , January 2017

Introducing genetic changes into mosquito populations could be key to effective malaria control.

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Blog – 10 May 2017

The New Yorker, Rewriting the code of life, January 2017

Through DNA editing, researchers hope to alter the genetic destiny of species and eliminate diseases.

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Blog – 10 May 2017

Nature, ‘Gene drive’ moratorium shot down at UN biodiversity meeting, January 2017

Freeze on genetic technology would have been a disaster, say scientists, but activists plan to renew the fight.

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Publication – 03 May 2017

Discussion paper of the Australian Academy of Science on synthetic gene drives in Australia

Discussion paper of the Australian Academy of Science on synthetic gene drives in Australia.  ...

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Publication – 03 May 2017

The High Council for Biotechnology (HCB) published its views on the use of genetically modified mosquitoes for vector control

The High Council for Biotechnology (HCB) published its views on the use of genetically modified mosquitoes for vector control. Paris, 31 May 2017  ...

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Publication – 03 May 2017

Professor Austin Burt has been awarded a President’s Medal for his work engaging the public in malaria-control projects across sub-Saharan Africa

Professor Austin Burt has been awarded a President’s Medal for his work engaging the public in malaria-control projects across sub-Saharan Africa.  ...

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Media Coverage – 24 April 2017

Keystone Symposia SciTalk 2017: Krystal Birungi

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Blog – 20 February 2017

Our team development

...team expansion was to include stakeholder engagement officers at this still very early stage to co-develop the technology and gain stakeholder buy in localy, nationaly and internationaly. Our team has...

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Publication – 18 December 2016

Impact of mosquito gene drive on malaria elimination in a computational model with explicit spatial and temporal dynamics

Impact of mosquito gene drive on malaria elimination in a computational model with explicit spatial and temporal dynamics...

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Publication – 03 December 2016

Use of Gene Drive technology in Mosquitoes to reduce the burden of malaria in Africa: A systematic evaluation of the risks

Use of Gene Drive technology in Mosquitoes to reduce the burden of malaria in Africa: A systematic evaluation of the risks  ...

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Publication – 03 November 2016

WHO World Malaria Report 2016

WHO World Malaria Report 2016  ...

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Blog – 14 October 2016

How to Develop This Cutting-Edge Genetic Research Responsibly

From ancient soothsayers to Wall Street stock pickers, humans have always yearned to be able to tell the future. The ability, needless to say, has mostly been overstated.

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Blog – 14 October 2016

Mosquitoes Are Deadly, So Why Not Kill Them All?

The death toll from diseases carried by mosquitoes is so huge that scientists are working on a radical idea. Why not eradicate them?

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Blog – 11 October 2016

New report highlights ethical questions linked to genome editing

...we look forward to more coming from the Council in the coming months. For a good overview of the issues at stake, look at the short (or long!) version online...

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Publication – 03 October 2016

Mapping the End of Malaria

Mapping the End of Malaria  ...

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Publication – 18 September 2016

Comparison of Model Predictions and Laboratory Observations of Transgene Frequencies in Continuously-Breeding Mosquito Populations

Comparison of Model Predictions and Laboratory Observations of Transgene Frequencies in Continuously-Breeding Mosquito Populations...

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Publication – 04 September 2016

Genome Editing: an ethical review by Nuffield Council on Bioethics

Genome Editing: an ethical review by Nuffield Council on Bioethics

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Publication – 18 August 2016

A CRISPR-Cas9 sex-ratio distortion system for genetic control

A CRISPR-Cas9 sex-ratio distortion system for genetic control...

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Publication – 04 July 2016

Gene Drives on the Horizon: Advancing Science, Navigating Uncertainty, and Aligning Research with Public Values

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Blog – 26 April 2016

Ending Malaria For Good

Early in my career, I was galvanized by a disease that ravaged my country and many others around the world: malaria.

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Blog – 26 April 2016

The Extinction Invention

Malaria kills half a million people each year, mostly children in tropical Africa. The price tag for eradicating the disease is estimated at more than $100 billion over 15 years.

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Blog – 26 April 2016

Nature special report on Crispr

Researchers the world over are fast adopting CRISPR-Cas9 to tinker with the genomes of humans, viruses, bacteria, animals and plants. Nature brings together research, reporting and expert opinion to keep...

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Publication – 18 April 2016

Gene drive through a landscape: Reaction-diffusion models of population suppression and elimination by a sex ratio distorter

Gene drive through a landscape: Reaction-diffusion models of population suppression and elimination by a sex ratio distorter...

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Publication – 18 March 2016

United Nations Foundation – SDG Goal 3: Ensure healthy lives and promote well-being for all at all ages

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Publication – 18 January 2016

A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae

A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae...

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Publication – 03 January 2016

United Nations Foundation – Sustainable Development Goals

UN Foundation – Sustainable Development Goals...

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A photo of one person lying on a bed, and a woman sitting beside them. The two people and the bed are covered by a large blue mosquito-prevention net

Media Coverage – 21 December 2015

Gene Drives Offer New Hope Against Diseases and Crop Pests

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Blog – 17 December 2015

Stepping up GM insect research a ‘moral duty’ for UK says Lords committee

Report concludes new technologies could save lives from diseases such as malaria, but says development is slowed by inadequate regulatory system

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Blog – 17 December 2015

Gene-Editing Technology Could Help Eradicate Malaria, Study Shows

A groundbreaking but controversial new gene-editing technology is accelerating a push to eradicate malaria, with scientists recently identifying two ways to block mosquitoes from transmitting the killer disease.

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Publication – 01 December 2015

Rapport de l’OMS sur le paludisme dans le monde 2015

WHO World Malaria Report 2015  ...

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Blog – 02 November 2015

Eradicating disease

To exterminate a living species by accident is normally frowned on. To do so deliberately might thus seem an extraordinary sin. But if that species is Plasmodium falciparum, the sin...

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Publication – 03 October 2015

Professor Austin Burt talks about the Capabilities and Tradeoffs of Gene Drive Techniques at The National Academy of Sciences

   ...

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Publication – 04 September 2015

From Aspiration to Action: What will it take to end malaria?

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News – 25 August 2015

Science Magazine, “Safeguarding gene drive experiments in the laboratory”, July 2015

Multiple strategies are needed to ensure safe gene drive experiments.

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News – 04 August 2015

BBC, “GM lab mosquitoes may aid malaria fight”, June 2014

Scientists have created mosquitoes that produce 95% male offspring, with the aim of helping control malaria. Flooding cages of normal mosquitoes with the new strain caused a shortage of females...

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News – 04 August 2015

Sky News “ New GM Mosquito ‘Could Help Defeat Malaria’, June 2014 (broadcast and online)

Scientists believe a new strain of mosquito that produces almost entirely male offspring could turn the tables in the fight against malaria.

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News – 04 August 2015

Al Jazeera News, Breakthrough claimed in malaria eradication, June 2014 (broadcast and online)

UK scientists think genetic modification will help check female population of mosquito species that spreads the disease.

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News – 04 August 2015

Royal Society Pfizer Award for IVCC partner, Nov. 4, 2013

A long-time collaborator of IVCC and LSTM has been awarded this year’s Royal Society Pfizer Award for his malaria research. Dr Abdoulaye Diabate, who is investigating the mating systems of...

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News – 04 August 2015

Imperial College, “Scientists prove new technology to control malaria-carrying mosquitoes”, April 2011

In today’s study, published in Nature, researchers from Imperial College London and the University of Washington, Seattle have demonstrated how some genetic changes can be introduced into large laboratory mosquito...

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News – 04 August 2015

Guardian, “Scientists create GM mosquitoes to fight malaria and save thousands of lives”, October 2005

Genetically modified mosquitoes could soon be released into the wild in an attempt to combat malaria. Scientists at Imperial College London, who created the GM insects, say they could wipe...

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Publication – 03 July 2015

United Nations – Millennium Development Goals Report 2015

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Publication – 02 July 2015

Speacial report FT Health: Combating Malaria by Financial Times

Financial Times

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Blog – 05 May 2015

Fight intensifies against malaria

...or the urban shanties of Haiti, new tools and tactics are being used to counter the spread of the disease and to alleviate its huge economic and human costs. http://www.ft.com/intl/cms/s/0/73b423ce-d3cc-11e4-99bd-00144feab7de.html#axzz3YovVBSPa...

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Blog – 05 May 2015

World Malaria Day: call to close gaps in prevention and treatment to defeat malaria

...and treatment of malaria. Despite dramatic declines in malaria cases and deaths since 2000, more than half a million lives are still lost to this preventable disease each year. http://www.who.int/mediacentre/news/releases/2015/world-malaria-day-2015/en/...

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Blog – 05 May 2015

Invest in the Future, Defeat Malaria: My Stroll With Dr Fatoumata Nafo-Traore

Dr Fatoumata Nafo-Traore, the Executive Director of the Roll Back Malaria Partnership talks aboutmalaria. Dr. Nafo-Traore has more than 25 years of experience in public health, both in her native...

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Blog – 05 May 2015

Malaria kills 1,200 children a day: UNICEF

UNICEF’s ‘Facts about Malaria and Children’ shows the extensive impact of the disease on children and on pregnant women around the world. This year’s World Malaria Day theme is “Invest...

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Blog – 05 May 2015

Time has come to cast net wider as pesticide resistance grows

The humble lightbulb is not often counted among the tools used to fight infectious disease. But, as questions hang over the efficacy of the insecticide-treated mosquito net, some argue that...

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Blog – 05 May 2015

World malaria day quiz

Half the world’s population is at risk from malaria, but how much do you know about the disease? Test your knowledge with this quiz created by Malaria No More...

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Blog – 05 May 2015

We Can Eradicate Malaria—Within a Generation

Bill Gates believes it is not only possible to eradicate malaria, he believes is necessary. On this blog post, he shares the strategy he proposes to achieve this mission.

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Blog – 05 May 2015

Delivery of new anti-malaria drugs to developing countries is vital in fight against the disease

...April. Medicines for Malaria Venture (MMV), a public-private partnership that seeks to develop and facilitate the delivery of quality anti-malaria drugs at affordable prices to people in developing countries. http://www.pharmaceutical-journal.com/opinion/qa/david-reddy-delivery-of-new-anti-malaria-drugs-to-developing-countries-is-vital-in-fight-against-the-disease/20068403.article...

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Publication – 18 February 2015

Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes.

Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes....

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Publication – 04 February 2015

Malaria: the last mile by Malaria Consortium

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Publication – 18 June 2014

A synthetic sex ratio distortion system in the human malaria mosquito

A synthetic sex ratio distortion system in the human malaria mosquito

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Publication – 18 June 2014

A synthetic sex ratio distortion system for the control of the human malaria mosquito

A synthetic sex ratio distortion system for the control of the human malaria mosquito

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Publication – 18 May 2014

Site-specific genetic engineering of the Anopheles gambiae Y chromosome

Site-specific genetic engineering of the Anopheles gambiae Y chromosome...

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Publication – 05 November 2013

Infertility resulting from transgenic I-PpoI male Anopheles gambiae in large cage trials

Infertility resulting from transgenic I-PpoI male Anopheles gambiae in large cage trials. T A Klein 1 , N Windbichler, A Deredec, A Burt, M Q Benedict...

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Publication – 18 July 2013

Modelling the spatial spread of a homing endonuclease gene in a mosquito population

Modelling the spatial spread of a homing endonuclease gene in a mosquito population

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Publication – 18 November 2012

Mosquito ecology and control of malaria

Mosquito ecology and control of malaria J. Anim. Ecol. 82(1):15-25

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Publication – 21 October 2011

Requirements for effective malaria control with homing endonuclease genes

Deredec A, Godfray HC, Burt A “Requirements for effective malaria control with homing endonuclease genes” Proc. Natl. Acad. Sci. USA 108(43):E874-80...

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Publication – 14 April 2011

Tapping natural reservoirs of homing endonucleases for targeted gene modification

Tapping natural reservoirs of homing endonucleases for targeted gene modification

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Publication – 14 April 2011

A synthetic homing endonuclease-based gene drive system in the human malaria mosquito

A synthetic homing endonuclease-based gene drive system in the human malaria mosquito

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Publication – 14 October 2005

An Anopheles transgenic sexing strain for vector control

Catteruccia F, Benton JP, Crisanti A “An Anopheles transgenic sexing strain for vector control” Nature Biotechnology (2005) 23, 1414 – 1417...

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